FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969255718> ?p ?o ?g. }

• W1969255718 endingPage "560" @default.
• W1969255718 startingPage "556" @default.
• W1969255718 abstract "Objective To compare the effects of the opioid antagonist, naloxone, on fluid ingestion in young and older males, in order to estimate the role of the opioid system in hypodipsia of older men. Design Single-blinded, randomized, cross-over, placebo-controlled study. Setting Outpatient Department of Veterans Affairs. Study Participants Sixteen young subjects (aged 23 to 39) and eight older subjects (aged 69 to 75). All subjects were healthy, community-dwelling, non-smoking men, on no medications. Intervention Subjects were randomized to receive either placebo or naloxone on day one. Whichever substance the subject did not receive was given on day two with days one and two separated by at least a 2-week washout period. Main Outcome Measures Fluid intake after overnight food and fluid deprivation, with placebo or naloxone injected in the morning. Results After overnight fluid deprivation, older individuals consumed 29% less fluid in 2 hours compared with younger individuals (ns). After overnight fluid deprivation and injection with naloxone 100 μg/kg, fluid intake was diminished by 42% (P < 0.05) in young subjects compared with placebo, but only by 7% (ns) in older subjects. Subjective ratings did not differ significantly between young and old subjects. Conclusions These preliminary data suggest that the opioid system plays a role in the drinking response in young subjects while failing to alter fluid intake in older subjects. Hypodipsia in older individuals may be due to a deficit in the opioid drinking drive." @default.
• W1969255718 created "2016-06-24" @default.
• W1969255718 creator A5006935353 @default.
• W1969255718 creator A5050614982 @default.
• W1969255718 date "1992-06-01" @default.
• W1969255718 modified "2023-10-17" @default.
• W1969255718 title "Role of the Opioid System in the Hypodipsia Associated with Aging" @default.
• W1969255718 cites W1874343805 @default.
• W1969255718 cites W1963966563 @default.
• W1969255718 cites W1969365907 @default.
• W1969255718 cites W1975264659 @default.
• W1969255718 cites W1977029792 @default.
• W1969255718 cites W198044234 @default.
• W1969255718 cites W1982335594 @default.
• W1969255718 cites W1983480228 @default.
• W1969255718 cites W1984799984 @default.
• W1969255718 cites W1989397378 @default.
• W1969255718 cites W1996292339 @default.
• W1969255718 cites W2002735721 @default.
• W1969255718 cites W2008772146 @default.
• W1969255718 cites W2009054779 @default.
• W1969255718 cites W2012778218 @default.
• W1969255718 cites W2015118888 @default.
• W1969255718 cites W2020576511 @default.
• W1969255718 cites W2025147543 @default.
• W1969255718 cites W2028998014 @default.
• W1969255718 cites W2029871821 @default.
• W1969255718 cites W2033679621 @default.
• W1969255718 cites W2037483809 @default.
• W1969255718 cites W2039983052 @default.
• W1969255718 cites W2046364059 @default.
• W1969255718 cites W2051329780 @default.
• W1969255718 cites W2057462579 @default.
• W1969255718 cites W2070316919 @default.
• W1969255718 cites W2078718738 @default.
• W1969255718 cites W2080018127 @default.
• W1969255718 cites W2093838313 @default.
• W1969255718 cites W2332024717 @default.
• W1969255718 cites W2340435310 @default.
• W1969255718 doi "https://doi.org/10.1111/j.1532-5415.1992.tb02102.x" @default.
• W1969255718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1587971" @default.
• W1969255718 hasPublicationYear "1992" @default.
• W1969255718 type Work @default.
• W1969255718 sameAs 1969255718 @default.
• W1969255718 citedByCount "64" @default.
• W1969255718 countsByYear W19692557182012 @default.
• W1969255718 countsByYear W19692557182014 @default.
• W1969255718 countsByYear W19692557182015 @default.
• W1969255718 countsByYear W19692557182017 @default.
• W1969255718 countsByYear W19692557182018 @default.
• W1969255718 countsByYear W19692557182019 @default.
• W1969255718 countsByYear W19692557182020 @default.
• W1969255718 countsByYear W19692557182022 @default.
• W1969255718 crossrefType "journal-article" @default.
• W1969255718 hasAuthorship W1969255718A5006935353 @default.
• W1969255718 hasAuthorship W1969255718A5050614982 @default.
• W1969255718 hasConcept C126322002 @default.
• W1969255718 hasConcept C142724271 @default.
• W1969255718 hasConcept C168563851 @default.
• W1969255718 hasConcept C170493617 @default.
• W1969255718 hasConcept C19720800 @default.
• W1969255718 hasConcept C204787440 @default.
• W1969255718 hasConcept C205545832 @default.
• W1969255718 hasConcept C27081682 @default.
• W1969255718 hasConcept C2775962371 @default.
• W1969255718 hasConcept C2778750930 @default.
• W1969255718 hasConcept C2779148768 @default.
• W1969255718 hasConcept C2781063702 @default.
• W1969255718 hasConcept C42219234 @default.
• W1969255718 hasConcept C71924100 @default.
• W1969255718 hasConceptScore W1969255718C126322002 @default.
• W1969255718 hasConceptScore W1969255718C142724271 @default.
• W1969255718 hasConceptScore W1969255718C168563851 @default.
• W1969255718 hasConceptScore W1969255718C170493617 @default.
• W1969255718 hasConceptScore W1969255718C19720800 @default.
• W1969255718 hasConceptScore W1969255718C204787440 @default.
• W1969255718 hasConceptScore W1969255718C205545832 @default.
• W1969255718 hasConceptScore W1969255718C27081682 @default.
• W1969255718 hasConceptScore W1969255718C2775962371 @default.
• W1969255718 hasConceptScore W1969255718C2778750930 @default.
• W1969255718 hasConceptScore W1969255718C2779148768 @default.
• W1969255718 hasConceptScore W1969255718C2781063702 @default.
• W1969255718 hasConceptScore W1969255718C42219234 @default.
• W1969255718 hasConceptScore W1969255718C71924100 @default.
• W1969255718 hasIssue "6" @default.
• W1969255718 hasLocation W19692557181 @default.
• W1969255718 hasLocation W19692557182 @default.
• W1969255718 hasOpenAccess W1969255718 @default.
• W1969255718 hasPrimaryLocation W19692557181 @default.
• W1969255718 hasRelatedWork W1973823807 @default.
• W1969255718 hasRelatedWork W2126273530 @default.
• W1969255718 hasRelatedWork W2321620707 @default.
• W1969255718 hasRelatedWork W2790838198 @default.
• W1969255718 hasRelatedWork W2797158262 @default.
• W1969255718 hasRelatedWork W2909505011 @default.
• W1969255718 hasRelatedWork W2922725244 @default.
• W1969255718 hasRelatedWork W2948003212 @default.
• W1969255718 hasRelatedWork W3171387315 @default.

• next