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- W1969283334 abstract "A 62-year-old presents with angina. He has been genotyped for a panel of drug metabolism enzymes through a direct-to-consumer genetics company. His results reveal a CYP2C19 *2/*2 genotype with a warning that poor metabolizers (PMs) may have “lack of therapeutic effect of clopidogrel (Plavix), resulting from failure to generate the active form of the drug.” Stress testing suggests significant ischemic burden with consequent need for percutaneous coronary intervention (PCI), possible stent placement, and antiplatelet therapy. Clinical Pharmacology & Therapeutics (2011) 89 3, 455–459. doi:10.1038/clpt.2010.316" @default.
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- W1969283334 date "2011-01-26" @default.
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- W1969283334 title "Pharmacogenetics and Clopidogrel Response in Patients Undergoing Percutaneous Coronary Interventions" @default.
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- W1969283334 doi "https://doi.org/10.1038/clpt.2010.316" @default.
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