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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969291457> ?p ?o ?g. }

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• W1969291457 abstract "Linezolid (LZD)-induced myelosuppression has been reported in adults; however, LZD-induced pure red cell precursor toxicity rarely occurs. A 2-year-old boy diagnosed with infective endocarditis by Streptococcus mitis received LZD after developing resistance to multiple antibiotics. Although his infective symptoms were improved by LZD, progressive anemia was noticed 2 weeks after LZD therapy. Four weeks after LZD administration, his hemoglobin level was 6.5 g/dL and reticulocytes less than 0.1%. Bone marrow examination revealed markedly decreased erythropoiesis with cytoplasmic vacuolation of erythroblasts. Anemia recovered 19 days after cessation of LZD. Elevated protoporphyrin and a high LZD level in the blood suggested that mitochondrial disturbance by high-dose and long-term treatment with LZD may have been responsible for LZD-induced pure red cell precursor toxicity." @default.
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• W1969291457 date "2009-09-01" @default.
• W1969291457 modified "2023-10-16" @default.
• W1969291457 title "Pure Red Cell Precursor Toxicity by Linezolid in a Pediatric Case" @default.
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• W1969291457 doi "https://doi.org/10.1097/mph.0b013e3181b1ed42" @default.
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