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- W1969295220 abstract "No AccessJournal of UrologyTestis/Cryptorchidism1 Oct 2004IS ADOLESCENT VARICOCELE A PROGRESSIVE DISEASE PROCESS? DAVID A. DIAMOND, DAVID ZURAKOWSKI, ANTHONY ATALA, STUART B. BAUER, JOSEPH G. BORER, BARTLEY G. CILENTO, HARRIET PALTIEL, CRAIG A. PETERS, and ALAN B. RETIK DAVID A. DIAMONDDAVID A. DIAMOND More articles by this author , DAVID ZURAKOWSKIDAVID ZURAKOWSKI More articles by this author , ANTHONY ATALAANTHONY ATALA More articles by this author , STUART B. BAUERSTUART B. BAUER More articles by this author , JOSEPH G. BORERJOSEPH G. BORER More articles by this author , BARTLEY G. CILENTOBARTLEY G. CILENTO More articles by this author , HARRIET PALTIELHARRIET PALTIEL More articles by this author , CRAIG A. PETERSCRAIG A. PETERS More articles by this author , and ALAN B. RETIKALAN B. RETIK More articles by this author View All Author Informationhttps://doi.org/10.1097/01.ju.0000138375.49016.62AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We determined whether there was evidence of progression in either varicocele grade or testicular volume differentials over time in our adolescent varicocele population. Materials and Methods: A total of 41 boys 7.3 to 19 years old (mean age 13.7, SD 2.5) were seen at sequential visits. At each visit varicocele grade was determined by the attending urologist and ultrasound calculated testicular volume differential was determined by an attending ultrasonographer. A senior staff statistician performed statistical analysis of the sequential data. Results: The varicocele grade data were analyzed using the nonparametric Wilcoxon test and no significant evidence of progression on sequential visits was demonstrated. Similarly, the serial volume differential data were assessed using the paired t test and no significant evidence for progression of testicular volume differentials was demonstrated. Conclusions: In our study population neither varicocele grade nor change in testicular volume differentials increased over time in a statistically significant manner. These results argue against the concept that adolescent varicocele is a progressive disease process. References 1 : Effects of varicocele on male fertility. Hum Reprod Update2001; 7: 59. Google Scholar 2 : Varicocele size and results of varicocelectomy in selected subfertile men with varicocele. Fertil Steril1970; 21: 606. Google Scholar 3 : Comparative assessment of pediatric testicular volume: orchidometer versus ultrasound. J Urol2000; 164: 1111. Link, Google Scholar 4 : Statistical Methods in Medical Research. Oxford, England: Blackwell Science2002: 698. Google Scholar 5 : Effects of varicocelectomy on testis volume and semen parameters in adolescence: a randomized prospective study. Nagoya J Med Sci1995; 58: 128. Google Scholar 6 : Surgical repair of varicocele at puberty: preventive treatment for fertility improvement. J Urol1988; 139: 562. Link, Google Scholar 7 : Effects of varicocele treatment in adolescents: a randomized study. Fertil Steril1992; 58: 756. Google Scholar 8 : Repair vs observation in adolescent varicocele: a prospective study. J Urol1997; 158: 1128. Link, Google Scholar From the Departments of Urology and Radiology, Children's Hospital, Harvard Medical School, Boston, Massachusetts© 2004 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited ByFaasse M (2018) Re: Semen Parameters in Adolescents with Varicocele: Association with Testis Volume Differential and Total Testis VolumeJournal of Urology, VOL. 195, NO. 2, (527-528), Online publication date: 1-Feb-2016.Kurtz M, Zurakowski D, Rosoklija I, Bauer S, Borer J, Johnson K, Migliozzi M and Diamond D (2015) Semen Parameters in Adolescents with Varicocele: Association with Testis Volume Differential and Total Testis VolumeJournal of Urology, VOL. 193, NO. 5S, (1843-1847), Online publication date: 1-May-2015.Christman M, Zderic S, Canning D and Kolon T (2018) Active Surveillance of the Adolescent with Varicocele: Predicting Semen Outcomes from UltrasoundJournal of Urology, VOL. 191, NO. 5, (1401-1406), Online publication date: 1-May-2014.Poon S, Gjertson C, Mercado M, Raimondi P, Kozakowski K and Glassberg K (2018) Testicular Asymmetry and Adolescent Varicoceles Managed ExpectantlyJournal of Urology, VOL. 183, NO. 2, (731-734), Online publication date: 1-Feb-2010.Castagnetti M (2010) Editorial CommentJournal of Urology, VOL. 184, NO. 4S, (1732-1732), Online publication date: 1-Oct-2010.Castagnetti M (2008) Editorial CommentJournal of Urology, VOL. 180, NO. 4S, (1656-1656), Online publication date: 1-Oct-2008. Volume 172Issue 4 Part 2October 2004Page: 1746-1748 Advertisement Copyright & Permissions© 2004 by American Urological Association, Inc.KeywordsadolescentvaricoceleMetricsAuthor Information DAVID A. DIAMOND More articles by this author DAVID ZURAKOWSKI More articles by this author ANTHONY ATALA More articles by this author STUART B. BAUER More articles by this author JOSEPH G. BORER More articles by this author BARTLEY G. CILENTO More articles by this author HARRIET PALTIEL More articles by this author CRAIG A. PETERS More articles by this author ALAN B. RETIK More articles by this author Expand All Advertisement PDF DownloadLoading ..." @default.
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