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- W1969330008 abstract "Alzheimer's disease (AD) is a neurodegenerative disease that inhibits cognitive functions and has no cure. This report reviews the current diagnostic standards for AD with an emphasis on early diagnosis using the cerebrospinal fluid (CSF) biomarkers amyloid-beta, t-tau, and p-tau and fluorodeoxyglucose positron emission tomography imaging. Abnormal levels of these CSF biomarkers and decreased cerebral uptake of glucose have recently been used in the early diagnosis of AD in experimental studies. These promising biomarkers can be measured using immunoassays performed in singleplex or multiplex formats. Although presently, there are no Food and Drug Administration-approved in vitro diagnostics (IVDs) for early detection of AD, a multiplex immunoassay measuring a panel of promising AD biomarkers in CSF may be a likely IVD candidate for the clinical AD diagnostic market. Specifically, the INNO-BIA AlzBio3 immunoassay kit, performed using bead arrays on the xMAP Luminex analyzer, allows simultaneous quantification of amyloid-beta, t-tau, and p-tau biomarkers. AD biomarkers can also be screened using enzyme-linked immunosorbent assays that are offered as laboratory-developed tests." @default.
- W1969330008 created "2016-06-24" @default.
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- W1969330008 date "2015-10-01" @default.
- W1969330008 modified "2023-10-13" @default.
- W1969330008 title "Biomarkers in the Diagnosis and Prognosis of Alzheimer’s Disease" @default.
- W1969330008 cites W139300322 @default.
- W1969330008 cites W1484920908 @default.
- W1969330008 cites W1490756559 @default.
- W1969330008 cites W1600125081 @default.
- W1969330008 cites W1616122655 @default.
- W1969330008 cites W1693283493 @default.
- W1969330008 cites W1761370356 @default.
- W1969330008 cites W1816679421 @default.
- W1969330008 cites W1829865020 @default.
- W1969330008 cites W1964869332 @default.
- W1969330008 cites W1966720891 @default.
- W1969330008 cites W1968512862 @default.
- W1969330008 cites W1969787718 @default.
- W1969330008 cites W1971029402 @default.
- W1969330008 cites W1982884883 @default.
- W1969330008 cites W1984737558 @default.
- W1969330008 cites W1985115107 @default.
- W1969330008 cites W1987909254 @default.
- W1969330008 cites W1990293508 @default.
- W1969330008 cites W1996981671 @default.
- W1969330008 cites W2000816306 @default.
- W1969330008 cites W2001010891 @default.
- W1969330008 cites W2005755021 @default.
- W1969330008 cites W2017079501 @default.
- W1969330008 cites W2021370614 @default.
- W1969330008 cites W2025036095 @default.
- W1969330008 cites W2032169907 @default.
- W1969330008 cites W2034286717 @default.
- W1969330008 cites W2035000249 @default.
- W1969330008 cites W2035466313 @default.
- W1969330008 cites W2036362108 @default.
- W1969330008 cites W2043224889 @default.
- W1969330008 cites W2043583138 @default.
- W1969330008 cites W2044614452 @default.
- W1969330008 cites W2045311514 @default.
- W1969330008 cites W2052041752 @default.
- W1969330008 cites W2054388625 @default.
- W1969330008 cites W2057236704 @default.
- W1969330008 cites W2059876510 @default.
- W1969330008 cites W2060240841 @default.
- W1969330008 cites W2065380426 @default.
- W1969330008 cites W2065419421 @default.
- W1969330008 cites W2067600736 @default.
- W1969330008 cites W2069121057 @default.
- W1969330008 cites W2071068165 @default.
- W1969330008 cites W2073589898 @default.
- W1969330008 cites W2077699648 @default.
- W1969330008 cites W2086523105 @default.
- W1969330008 cites W2087309100 @default.
- W1969330008 cites W2091934374 @default.
- W1969330008 cites W2096278562 @default.
- W1969330008 cites W2096321911 @default.
- W1969330008 cites W2100353404 @default.
- W1969330008 cites W2101077392 @default.
- W1969330008 cites W2102320098 @default.
- W1969330008 cites W2103825172 @default.
- W1969330008 cites W2103976492 @default.
- W1969330008 cites W2105599318 @default.
- W1969330008 cites W2105704879 @default.
- W1969330008 cites W2108475007 @default.
- W1969330008 cites W2108949684 @default.
- W1969330008 cites W2109417691 @default.
- W1969330008 cites W2109513739 @default.
- W1969330008 cites W2111420081 @default.
- W1969330008 cites W2120522615 @default.
- W1969330008 cites W2124670646 @default.
- W1969330008 cites W2127635525 @default.
- W1969330008 cites W2131215891 @default.
- W1969330008 cites W2134736198 @default.
- W1969330008 cites W2137570301 @default.
- W1969330008 cites W2138938304 @default.
- W1969330008 cites W2143967388 @default.
- W1969330008 cites W2146788881 @default.
- W1969330008 cites W2153273744 @default.
- W1969330008 cites W2161222316 @default.
- W1969330008 cites W2161737267 @default.
- W1969330008 cites W2166505837 @default.
- W1969330008 cites W2168283959 @default.
- W1969330008 cites W2171250577 @default.
- W1969330008 cites W2511246053 @default.
- W1969330008 cites W2752287204 @default.
- W1969330008 doi "https://doi.org/10.1177/2211068214559979" @default.
- W1969330008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25424384" @default.
- W1969330008 hasPublicationYear "2015" @default.
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