Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969352235> ?p ?o ?g. }
- W1969352235 abstract "Regenerative mechanisms after surgical injury have been studied in many organs but not in the kidney. Studying surgical injury may provide new insights into mechanisms of kidney regeneration. In rodent models, extrarenal tissues adhere to surgical kidney wound and interfere with healing. We hypothesized that this can be prevented by wrapping injured kidney in a plastic pouch. Adult rats tolerated 5/6 nephrectomy with pouch application well. Histological analysis demonstrates that application of the pouch effectively prevented formation of adhesions and induced characteristic wound healing manifested by formation of granulation tissue. Additionally, selected tubules of the wounded kidney extended into the granulation tissue forming branching tubular epithelial outgrowths (TEOs) without terminal differentiation. Tubular regeneration outside of renal parenchyma was not previously observed and suggests previously unrecognized capacity for regeneration. Our model provides a novel approach to study kidney wound healing." @default.
- W1969352235 created "2016-06-24" @default.
- W1969352235 creator A5008626010 @default.
- W1969352235 creator A5020410166 @default.
- W1969352235 creator A5034644031 @default.
- W1969352235 creator A5048437118 @default.
- W1969352235 creator A5056600680 @default.
- W1969352235 creator A5059683938 @default.
- W1969352235 creator A5078222975 @default.
- W1969352235 date "2013-10-08" @default.
- W1969352235 modified "2023-09-26" @default.
- W1969352235 title "A Novel Model of Surgical Injury in Adult Rat Kidney: A “Pouch Model”" @default.
- W1969352235 cites W1835009115 @default.
- W1969352235 cites W1972324645 @default.
- W1969352235 cites W1974805319 @default.
- W1969352235 cites W1979613923 @default.
- W1969352235 cites W1983939518 @default.
- W1969352235 cites W1986829962 @default.
- W1969352235 cites W1991164124 @default.
- W1969352235 cites W2000714884 @default.
- W1969352235 cites W2002397995 @default.
- W1969352235 cites W2008434851 @default.
- W1969352235 cites W2015274943 @default.
- W1969352235 cites W2022422012 @default.
- W1969352235 cites W2026674590 @default.
- W1969352235 cites W2035080881 @default.
- W1969352235 cites W2055346060 @default.
- W1969352235 cites W2062099067 @default.
- W1969352235 cites W2069478265 @default.
- W1969352235 cites W2073420830 @default.
- W1969352235 cites W2077973767 @default.
- W1969352235 cites W2081282575 @default.
- W1969352235 cites W2081580127 @default.
- W1969352235 cites W2089245533 @default.
- W1969352235 cites W2099296620 @default.
- W1969352235 cites W2100223622 @default.
- W1969352235 cites W2102484924 @default.
- W1969352235 cites W2111947308 @default.
- W1969352235 cites W2114058685 @default.
- W1969352235 cites W2120096411 @default.
- W1969352235 cites W2146713188 @default.
- W1969352235 cites W2148479501 @default.
- W1969352235 cites W2154296848 @default.
- W1969352235 cites W2155182804 @default.
- W1969352235 cites W2160590108 @default.
- W1969352235 cites W2165830726 @default.
- W1969352235 cites W2172053176 @default.
- W1969352235 cites W2243393341 @default.
- W1969352235 cites W2342826420 @default.
- W1969352235 cites W2492099326 @default.
- W1969352235 cites W4231762600 @default.
- W1969352235 doi "https://doi.org/10.1038/srep02890" @default.
- W1969352235 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3792422" @default.
- W1969352235 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24100472" @default.
- W1969352235 hasPublicationYear "2013" @default.
- W1969352235 type Work @default.
- W1969352235 sameAs 1969352235 @default.
- W1969352235 citedByCount "3" @default.
- W1969352235 countsByYear W19693522352016 @default.
- W1969352235 countsByYear W19693522352017 @default.
- W1969352235 countsByYear W19693522352021 @default.
- W1969352235 crossrefType "journal-article" @default.
- W1969352235 hasAuthorship W1969352235A5008626010 @default.
- W1969352235 hasAuthorship W1969352235A5020410166 @default.
- W1969352235 hasAuthorship W1969352235A5034644031 @default.
- W1969352235 hasAuthorship W1969352235A5048437118 @default.
- W1969352235 hasAuthorship W1969352235A5056600680 @default.
- W1969352235 hasAuthorship W1969352235A5059683938 @default.
- W1969352235 hasAuthorship W1969352235A5078222975 @default.
- W1969352235 hasBestOaLocation W19693522351 @default.
- W1969352235 hasConcept C105702510 @default.
- W1969352235 hasConcept C126322002 @default.
- W1969352235 hasConcept C141071460 @default.
- W1969352235 hasConcept C142724271 @default.
- W1969352235 hasConcept C171056886 @default.
- W1969352235 hasConcept C196822366 @default.
- W1969352235 hasConcept C2776055305 @default.
- W1969352235 hasConcept C2780091579 @default.
- W1969352235 hasConcept C2780101441 @default.
- W1969352235 hasConcept C2780227381 @default.
- W1969352235 hasConcept C2780269544 @default.
- W1969352235 hasConcept C71924100 @default.
- W1969352235 hasConcept C86803240 @default.
- W1969352235 hasConcept C95444343 @default.
- W1969352235 hasConceptScore W1969352235C105702510 @default.
- W1969352235 hasConceptScore W1969352235C126322002 @default.
- W1969352235 hasConceptScore W1969352235C141071460 @default.
- W1969352235 hasConceptScore W1969352235C142724271 @default.
- W1969352235 hasConceptScore W1969352235C171056886 @default.
- W1969352235 hasConceptScore W1969352235C196822366 @default.
- W1969352235 hasConceptScore W1969352235C2776055305 @default.
- W1969352235 hasConceptScore W1969352235C2780091579 @default.
- W1969352235 hasConceptScore W1969352235C2780101441 @default.
- W1969352235 hasConceptScore W1969352235C2780227381 @default.
- W1969352235 hasConceptScore W1969352235C2780269544 @default.
- W1969352235 hasConceptScore W1969352235C71924100 @default.
- W1969352235 hasConceptScore W1969352235C86803240 @default.
- W1969352235 hasConceptScore W1969352235C95444343 @default.
- W1969352235 hasIssue "1" @default.
- W1969352235 hasLocation W19693522351 @default.