FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969353558> ?p ?o ?g. }

• W1969353558 endingPage "382" @default.
• W1969353558 startingPage "365" @default.
• W1969353558 abstract "Intracellular application of tritiated precursors by means of microiontophoresis was performed on nerve cells in isolated segmental ganglia of the leech ventral nerve cord. Incorporation as well as intra- and interneuronal transport were studied by autoradiography after injection of fucose, glucosamine, glycine, leucine, orotic acid and uridine. Within several minutes of intraneuronal injection the precursors were incorporated into macromolecules. Depending upon the tracer used, the radioactive material was distributed in a specific pattern over the cell somata and then released into the nerve processes. After application of orotic acid and uridine a transport of radioactive material, presumably RNA, could be observed in the processes of the injected neurons at a distance of about 200–500 μm. Fucose and glucosamine injection resulted in the most extended labeling of the nerve cell processes, indicating a transport rate of about 11 mm/day. When the radiochemicals were injected into one of the two electrically coupled giant nerve cells — the so-called Retzius cells (Rc) — a specific labeling not only of the injected Rc but also of the coupled but not injected Rc was found. Injection of protein or glycoprotein precursors into one Rc produced heavy labeling of both Rcs including their processes; a slight labeling of other ganglion compartments was only found after increasing the dosage of the amino acids glycine and leucine. With orotic acid and uridine this interneuronal transfer was confined to the electrically coupled Rc twin. Intracellular injection of one Rc with puromycin followed by injection of amino acids or fucose into the same Rc or into the coupled Rc resulted in an inhibition of precursor incorporation within the puromycin-injected Rc and an exclusive labeling of the coupled Rc, thus indicating that the precursors themselves were transferred. It is suggested that after microiontophoretic application an interneuronal transfer of relatively low molecular weight material takes place, probably across the low-resistance junction through which the Rcs are electrically coupled." @default.
• W1969353558 created "2016-06-24" @default.
• W1969353558 creator A5009219737 @default.
• W1969353558 creator A5053602039 @default.
• W1969353558 creator A5082018475 @default.
• W1969353558 date "1975-02-01" @default.
• W1969353558 modified "2023-09-26" @default.
• W1969353558 title "Transfer of radioactive material between electrically coupled neurons of the leech central nervous system" @default.
• W1969353558 cites W1459448442 @default.
• W1969353558 cites W1582796640 @default.
• W1969353558 cites W1844740521 @default.
• W1969353558 cites W1967430656 @default.
• W1969353558 cites W1968875442 @default.
• W1969353558 cites W1975974356 @default.
• W1969353558 cites W1977053371 @default.
• W1969353558 cites W1977414875 @default.
• W1969353558 cites W1978384008 @default.
• W1969353558 cites W1979619909 @default.
• W1969353558 cites W1980348648 @default.
• W1969353558 cites W1980585111 @default.
• W1969353558 cites W1981012632 @default.
• W1969353558 cites W1991190722 @default.
• W1969353558 cites W1991392398 @default.
• W1969353558 cites W2005811883 @default.
• W1969353558 cites W2010274928 @default.
• W1969353558 cites W2015436703 @default.
• W1969353558 cites W2021445156 @default.
• W1969353558 cites W2024753554 @default.
• W1969353558 cites W2028085408 @default.
• W1969353558 cites W2035740620 @default.
• W1969353558 cites W2040051395 @default.
• W1969353558 cites W2040449918 @default.
• W1969353558 cites W2047651845 @default.
• W1969353558 cites W2058958429 @default.
• W1969353558 cites W2066174870 @default.
• W1969353558 cites W2067796383 @default.
• W1969353558 cites W2068226823 @default.
• W1969353558 cites W2068952753 @default.
• W1969353558 cites W2073141574 @default.
• W1969353558 cites W2079987548 @default.
• W1969353558 cites W2085148475 @default.
• W1969353558 cites W2086243893 @default.
• W1969353558 cites W2088690257 @default.
• W1969353558 cites W2088975375 @default.
• W1969353558 cites W2090637744 @default.
• W1969353558 cites W2091654808 @default.
• W1969353558 cites W2093370136 @default.
• W1969353558 cites W2094595742 @default.
• W1969353558 cites W2101876650 @default.
• W1969353558 cites W2107650772 @default.
• W1969353558 cites W2137274676 @default.
• W1969353558 cites W2137836504 @default.
• W1969353558 cites W2141320842 @default.
• W1969353558 cites W2158798405 @default.
• W1969353558 cites W2166983044 @default.
• W1969353558 cites W2270283363 @default.
• W1969353558 cites W2314288216 @default.
• W1969353558 cites W2338244249 @default.
• W1969353558 cites W2407782954 @default.
• W1969353558 cites W2415575244 @default.
• W1969353558 cites W2416070870 @default.
• W1969353558 cites W2417812030 @default.
• W1969353558 cites W2424287624 @default.
• W1969353558 cites W2441506123 @default.
• W1969353558 cites W2469733403 @default.
• W1969353558 cites W4324262194 @default.
• W1969353558 cites W961383677 @default.
• W1969353558 doi "https://doi.org/10.1016/0006-8993(75)90759-3" @default.
• W1969353558 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1122378" @default.
• W1969353558 hasPublicationYear "1975" @default.
• W1969353558 type Work @default.
• W1969353558 sameAs 1969353558 @default.
• W1969353558 citedByCount "42" @default.
• W1969353558 countsByYear W19693535582013 @default.
• W1969353558 countsByYear W19693535582023 @default.
• W1969353558 crossrefType "journal-article" @default.
• W1969353558 hasAuthorship W1969353558A5009219737 @default.
• W1969353558 hasAuthorship W1969353558A5053602039 @default.
• W1969353558 hasAuthorship W1969353558A5082018475 @default.
• W1969353558 hasConcept C104317684 @default.
• W1969353558 hasConcept C108625454 @default.
• W1969353558 hasConcept C12554922 @default.
• W1969353558 hasConcept C185592680 @default.
• W1969353558 hasConcept C194575858 @default.
• W1969353558 hasConcept C2776841590 @default.
• W1969353558 hasConcept C2777756961 @default.
• W1969353558 hasConcept C2779530196 @default.
• W1969353558 hasConcept C2781259782 @default.
• W1969353558 hasConcept C515207424 @default.
• W1969353558 hasConcept C55493867 @default.
• W1969353558 hasConcept C67705224 @default.
• W1969353558 hasConcept C70192387 @default.
• W1969353558 hasConcept C79879829 @default.
• W1969353558 hasConcept C86803240 @default.
• W1969353558 hasConcept C95444343 @default.
• W1969353558 hasConceptScore W1969353558C104317684 @default.
• W1969353558 hasConceptScore W1969353558C108625454 @default.
• W1969353558 hasConceptScore W1969353558C12554922 @default.

• next