FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969371344> ?p ?o ?g. }

• W1969371344 endingPage "232" @default.
• W1969371344 startingPage "225" @default.
• W1969371344 abstract "The phrase reactive oxygen species covers a number of molecules and atoms, including the quintessential member of the group, O2-; singlet oxygen; H2O2; organic peroxides; and OONO-. While nitric oxide (NO) is also technically a member of the reactive oxygen species family, it is generally considered with a different class of compounds and will not be considered here. To our knowledge, there are currently no published data reporting the effects of reactive oxygen species on net transepithelial flux in the proximal nephron. However, there is evidence that OONO- regulates Na+/K+ adenosine triphosphatase (ATPase) activity as well as paracellular permeability. While it is easy to speculate that such an effect on the pump would decrease net transepithelial solute and water reabsorption, one cannot do so without knowing how other transporters are affected. O2- stimulates NaCl absorption by the thick ascending limb by activating protein kinase C and blunting the effects of NO. The effects of O2- on thick ascending limb NaCl absorption may be important for the initiation of salt-sensitive hypertension. To our knowledge, there are no published data concerning the role of reactive oxygen species in the regulation of solute absorption in either the distal convoluted tubule or the collecting duct. However, OONO- inhibits basolateral K+ channels in the cortical collecting duct, although the net effect of such inhibition is unknown.While the regulation of tubular transport by reactive oxygen species is important to overall salt and water balance, we know very little about where and how these regulators act along the nephron." @default.
• W1969371344 created "2016-06-24" @default.
• W1969371344 creator A5021025572 @default.
• W1969371344 creator A5077979393 @default.
• W1969371344 date "2003-11-01" @default.
• W1969371344 modified "2023-10-15" @default.
• W1969371344 title "The role of reactive oxygen species in the regulation of tubular function" @default.
• W1969371344 cites W1512089777 @default.
• W1969371344 cites W1530888481 @default.
• W1969371344 cites W1586099293 @default.
• W1969371344 cites W1589390349 @default.
• W1969371344 cites W1704317488 @default.
• W1969371344 cites W1964033398 @default.
• W1969371344 cites W1969260760 @default.
• W1969371344 cites W1975755721 @default.
• W1969371344 cites W1975887293 @default.
• W1969371344 cites W1977384496 @default.
• W1969371344 cites W1978002877 @default.
• W1969371344 cites W1981513678 @default.
• W1969371344 cites W1981755821 @default.
• W1969371344 cites W1982047009 @default.
• W1969371344 cites W1986430910 @default.
• W1969371344 cites W1989421333 @default.
• W1969371344 cites W2001952423 @default.
• W1969371344 cites W2007328856 @default.
• W1969371344 cites W2008102223 @default.
• W1969371344 cites W2020487030 @default.
• W1969371344 cites W2023093466 @default.
• W1969371344 cites W2037291567 @default.
• W1969371344 cites W2039950005 @default.
• W1969371344 cites W2047155389 @default.
• W1969371344 cites W2052771339 @default.
• W1969371344 cites W2077819931 @default.
• W1969371344 cites W2081330632 @default.
• W1969371344 cites W2093013713 @default.
• W1969371344 cites W2095399465 @default.
• W1969371344 cites W2103687576 @default.
• W1969371344 cites W2105291285 @default.
• W1969371344 cites W2109893157 @default.
• W1969371344 cites W2114879832 @default.
• W1969371344 cites W2116479368 @default.
• W1969371344 cites W2120358575 @default.
• W1969371344 cites W2123799914 @default.
• W1969371344 cites W2124942654 @default.
• W1969371344 cites W2132199758 @default.
• W1969371344 cites W2133838366 @default.
• W1969371344 cites W2137000100 @default.
• W1969371344 cites W2145353891 @default.
• W1969371344 cites W2147883571 @default.
• W1969371344 cites W2148626152 @default.
• W1969371344 cites W2159121840 @default.
• W1969371344 cites W2159992963 @default.
• W1969371344 cites W2168460845 @default.
• W1969371344 cites W2180840416 @default.
• W1969371344 cites W2184908421 @default.
• W1969371344 cites W2190317876 @default.
• W1969371344 cites W2320410254 @default.
• W1969371344 cites W2335927080 @default.
• W1969371344 cites W2337457656 @default.
• W1969371344 cites W2409457485 @default.
• W1969371344 cites W2412112832 @default.
• W1969371344 cites W2415538420 @default.
• W1969371344 cites W2418743811 @default.
• W1969371344 cites W4232451995 @default.
• W1969371344 cites W4250769951 @default.
• W1969371344 doi "https://doi.org/10.1046/j.0001-6772.2003.01203.x" @default.
• W1969371344 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14616238" @default.
• W1969371344 hasPublicationYear "2003" @default.
• W1969371344 type Work @default.
• W1969371344 sameAs 1969371344 @default.
• W1969371344 citedByCount "75" @default.
• W1969371344 countsByYear W19693713442012 @default.
• W1969371344 countsByYear W19693713442013 @default.
• W1969371344 countsByYear W19693713442014 @default.
• W1969371344 countsByYear W19693713442015 @default.
• W1969371344 countsByYear W19693713442016 @default.
• W1969371344 countsByYear W19693713442017 @default.
• W1969371344 countsByYear W19693713442018 @default.
• W1969371344 countsByYear W19693713442019 @default.
• W1969371344 countsByYear W19693713442020 @default.
• W1969371344 crossrefType "journal-article" @default.
• W1969371344 hasAuthorship W1969371344A5021025572 @default.
• W1969371344 hasAuthorship W1969371344A5077979393 @default.
• W1969371344 hasConcept C120882062 @default.
• W1969371344 hasConcept C12554922 @default.
• W1969371344 hasConcept C159641895 @default.
• W1969371344 hasConcept C178790620 @default.
• W1969371344 hasConcept C185592680 @default.
• W1969371344 hasConcept C2781231759 @default.
• W1969371344 hasConcept C41625074 @default.
• W1969371344 hasConcept C48349386 @default.
• W1969371344 hasConcept C519581460 @default.
• W1969371344 hasConcept C537181965 @default.
• W1969371344 hasConcept C540031477 @default.
• W1969371344 hasConcept C55493867 @default.
• W1969371344 hasConcept C56906281 @default.
• W1969371344 hasConcept C60903277 @default.
• W1969371344 hasConcept C86803240 @default.

• next