Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969372147> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W1969372147 endingPage "41" @default.
- W1969372147 startingPage "34" @default.
- W1969372147 abstract "Mild digestion of Serratia marcescens tryptophan synthase β2 subunit produces a modified β2 subunit (nicked β2). The nicked β2 subunit remains essentially intact and is immunochemically reactive with native β2 subunit antiserum. Denaturation of the nicked β2 subunit yields two principal peptide fragments whose minimum molecular weights are 29,500 and 13,400. Loss of enzyme activity is associated with the selective proteolysis. The enzyme cofactor pyridoxal phosphate binding site is on the larger fragment. Following separation of the fragments by urea-gel chromatography, the separated peptides retain immunological cross-reactivity with native β2 subunit antiserum. These fragments apparently represent two domains that comprise the native Holo β2 subunit. The immunochemical data suggest that these fragments, when isolated, can assume some tertiary structure and that they may exist as such prior to β monomer or β2 dimer assembly. The folded fragments may represent intermediates in the biosynthesis of the β2 subunit as has been suggested for the E. coli enzyme (A. Högberg-Raibaud and M. E. Goldberg, 1977, Proc. Nat. Acad. Sci. USA74, 442; Biochemistry16, 4014)." @default.
- W1969372147 created "2016-06-24" @default.
- W1969372147 creator A5074081076 @default.
- W1969372147 creator A5076224160 @default.
- W1969372147 creator A5080491452 @default.
- W1969372147 date "1979-03-01" @default.
- W1969372147 modified "2023-09-26" @default.
- W1969372147 title "Selective proteolysis of the β2 subunit of Serratia marcescens tryptophan synthase" @default.
- W1969372147 cites W1549596926 @default.
- W1969372147 cites W1571974428 @default.
- W1969372147 cites W1575847461 @default.
- W1969372147 cites W1576096225 @default.
- W1969372147 cites W1583468563 @default.
- W1969372147 cites W1625660792 @default.
- W1969372147 cites W1775749144 @default.
- W1969372147 cites W1833941111 @default.
- W1969372147 cites W1839020371 @default.
- W1969372147 cites W1855848627 @default.
- W1969372147 cites W2019244584 @default.
- W1969372147 cites W2072645500 @default.
- W1969372147 cites W2091177185 @default.
- W1969372147 cites W2100837269 @default.
- W1969372147 cites W2138920928 @default.
- W1969372147 cites W2242295414 @default.
- W1969372147 cites W4230808134 @default.
- W1969372147 cites W99574075 @default.
- W1969372147 doi "https://doi.org/10.1016/0003-9861(79)90005-5" @default.
- W1969372147 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/110267" @default.
- W1969372147 hasPublicationYear "1979" @default.
- W1969372147 type Work @default.
- W1969372147 sameAs 1969372147 @default.
- W1969372147 citedByCount "6" @default.
- W1969372147 crossrefType "journal-article" @default.
- W1969372147 hasAuthorship W1969372147A5074081076 @default.
- W1969372147 hasAuthorship W1969372147A5076224160 @default.
- W1969372147 hasAuthorship W1969372147A5080491452 @default.
- W1969372147 hasConcept C104292427 @default.
- W1969372147 hasConcept C104317684 @default.
- W1969372147 hasConcept C112243037 @default.
- W1969372147 hasConcept C178790620 @default.
- W1969372147 hasConcept C181199279 @default.
- W1969372147 hasConcept C185592680 @default.
- W1969372147 hasConcept C197957613 @default.
- W1969372147 hasConcept C2776706248 @default.
- W1969372147 hasConcept C2776834122 @default.
- W1969372147 hasConcept C2779546866 @default.
- W1969372147 hasConcept C2779882130 @default.
- W1969372147 hasConcept C2781307694 @default.
- W1969372147 hasConcept C515207424 @default.
- W1969372147 hasConcept C55493867 @default.
- W1969372147 hasConcept C71240020 @default.
- W1969372147 hasConceptScore W1969372147C104292427 @default.
- W1969372147 hasConceptScore W1969372147C104317684 @default.
- W1969372147 hasConceptScore W1969372147C112243037 @default.
- W1969372147 hasConceptScore W1969372147C178790620 @default.
- W1969372147 hasConceptScore W1969372147C181199279 @default.
- W1969372147 hasConceptScore W1969372147C185592680 @default.
- W1969372147 hasConceptScore W1969372147C197957613 @default.
- W1969372147 hasConceptScore W1969372147C2776706248 @default.
- W1969372147 hasConceptScore W1969372147C2776834122 @default.
- W1969372147 hasConceptScore W1969372147C2779546866 @default.
- W1969372147 hasConceptScore W1969372147C2779882130 @default.
- W1969372147 hasConceptScore W1969372147C2781307694 @default.
- W1969372147 hasConceptScore W1969372147C515207424 @default.
- W1969372147 hasConceptScore W1969372147C55493867 @default.
- W1969372147 hasConceptScore W1969372147C71240020 @default.
- W1969372147 hasIssue "1" @default.
- W1969372147 hasLocation W19693721471 @default.
- W1969372147 hasLocation W19693721472 @default.
- W1969372147 hasOpenAccess W1969372147 @default.
- W1969372147 hasPrimaryLocation W19693721471 @default.
- W1969372147 hasRelatedWork W1039389130 @default.
- W1969372147 hasRelatedWork W1971418776 @default.
- W1969372147 hasRelatedWork W1974264311 @default.
- W1969372147 hasRelatedWork W2000978079 @default.
- W1969372147 hasRelatedWork W2060915031 @default.
- W1969372147 hasRelatedWork W2063292893 @default.
- W1969372147 hasRelatedWork W2087717059 @default.
- W1969372147 hasRelatedWork W2106788995 @default.
- W1969372147 hasRelatedWork W2843789058 @default.
- W1969372147 hasRelatedWork W99077715 @default.
- W1969372147 hasVolume "193" @default.
- W1969372147 isParatext "false" @default.
- W1969372147 isRetracted "false" @default.
- W1969372147 magId "1969372147" @default.
- W1969372147 workType "article" @default.