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- W1969397241 abstract "The aim of this study was to identify the existence of anion-dependent Mg transport systems in cardiac muscle. DIDS-sensitive and anion-dependent (either Cl(-)(o) or NO(-)(3o)) increases in [Mg(2+)](i) occurred during Mg(2+) loading conditions. Much larger elevations of [Mg(2+)](i) occurred under Cl(-)(o)-free conditions with 0.1 mmol l(-1) DIDS, compared to Cl(-)(o) replacement alone. All these effects were abolished in Mg(2+)(o)-free medium. These data suggest a novel Mg(2+)-anion symport for Mg(2+) efflux against the electrochemical gradient that is fueled mostly by the efflux of an endogenous anion (HCO(-)(3)?), but with a small contribution from intracellular Cl(-) probably supplied via the Cl(-)-HCO(-)(3) exchanger." @default.
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- W1969397241 date "1999-10-01" @default.
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- W1969397241 title "A Novel DIDS-Sensitive, Anion-Dependent Mg2+ Efflux Pathway in Rat Ventricular Myocytes" @default.
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- W1969397241 doi "https://doi.org/10.1006/bbrc.1999.1490" @default.
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