Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969409728> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W1969409728 endingPage "325" @default.
- W1969409728 startingPage "316" @default.
- W1969409728 abstract "This study reports the presence of surprisingly frequent and often severe interstitial fibrosis in cigarette smokers with no clinical evidence of interstitial lung disease. Twenty-three lobectomy specimens excised for neoplasms, including 20 from smokers, were extensively sampled, and examined semi-quantitatively for interstitial fibrosis, fibroblast foci, peribronchiolar metaplasia, honey-comb change, emphysema, and respiratory bronchiolitis. Interstitial fibrosis involving greater than 25% of slides was identified in 12 of 20 smokers (60%), but in none of the three never-smokers. Three cases were classified as specific forms of interstitial lung disease, including one each of usual interstitial pneumonia, Langerhans cell histiocytosis, and asbestosis. The remaining 9 cases did not fit with a named interstitial lung disease and were considered to represent examples of smoking-related interstitial fibrosis. This lesion was characterized by varying degrees of alveolar septal widening by collagen deposition along with emphysema and respiratory bronchiolitis. The fibrosis occurred both in subpleural and in deeper parenchyma. It surrounded enlarged airspaces of emphysema, but it also involved non-emphysematous parenchyma. Clinical progression was not documented in any case, although follow-up was short. These observations highlight the spectrum of unexpected fibrosis that is frequently encountered in lobectomy specimens from cigarette smokers. Additional investigation will be required to determine the clinical significance of smoking-related interstitial fibrosis and its relationship, if any, to other smoking-related diseases. It is important, however, that smoking-related interstitial fibrosis be distinguished from specific forms of fibrosing lung disease that may be associated with poor prognoses, especially usual interstitial pneumonia." @default.
- W1969409728 created "2016-06-24" @default.
- W1969409728 creator A5007274277 @default.
- W1969409728 creator A5033206474 @default.
- W1969409728 creator A5034057439 @default.
- W1969409728 creator A5034537873 @default.
- W1969409728 date "2010-03-01" @default.
- W1969409728 modified "2023-09-27" @default.
- W1969409728 title "Clinically occult interstitial fibrosis in smokers: classification and significance of a surprisingly common finding in lobectomy specimens" @default.
- W1969409728 cites W1966600667 @default.
- W1969409728 cites W1974234058 @default.
- W1969409728 cites W1995385974 @default.
- W1969409728 cites W2041116306 @default.
- W1969409728 cites W2054523556 @default.
- W1969409728 cites W2055168512 @default.
- W1969409728 cites W2055305833 @default.
- W1969409728 cites W2069459077 @default.
- W1969409728 cites W2113427585 @default.
- W1969409728 cites W2113777102 @default.
- W1969409728 cites W2133863770 @default.
- W1969409728 doi "https://doi.org/10.1016/j.humpath.2009.09.003" @default.
- W1969409728 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20004953" @default.
- W1969409728 hasPublicationYear "2010" @default.
- W1969409728 type Work @default.
- W1969409728 sameAs 1969409728 @default.
- W1969409728 citedByCount "191" @default.
- W1969409728 countsByYear W19694097282012 @default.
- W1969409728 countsByYear W19694097282013 @default.
- W1969409728 countsByYear W19694097282014 @default.
- W1969409728 countsByYear W19694097282015 @default.
- W1969409728 countsByYear W19694097282016 @default.
- W1969409728 countsByYear W19694097282017 @default.
- W1969409728 countsByYear W19694097282018 @default.
- W1969409728 countsByYear W19694097282019 @default.
- W1969409728 countsByYear W19694097282020 @default.
- W1969409728 countsByYear W19694097282021 @default.
- W1969409728 countsByYear W19694097282022 @default.
- W1969409728 countsByYear W19694097282023 @default.
- W1969409728 crossrefType "journal-article" @default.
- W1969409728 hasAuthorship W1969409728A5007274277 @default.
- W1969409728 hasAuthorship W1969409728A5033206474 @default.
- W1969409728 hasAuthorship W1969409728A5034057439 @default.
- W1969409728 hasAuthorship W1969409728A5034537873 @default.
- W1969409728 hasConcept C126322002 @default.
- W1969409728 hasConcept C142724271 @default.
- W1969409728 hasConcept C150489694 @default.
- W1969409728 hasConcept C2777405647 @default.
- W1969409728 hasConcept C2777543607 @default.
- W1969409728 hasConcept C2777714996 @default.
- W1969409728 hasConcept C2778341716 @default.
- W1969409728 hasConcept C2778821649 @default.
- W1969409728 hasConcept C2779412668 @default.
- W1969409728 hasConcept C2780559512 @default.
- W1969409728 hasConcept C2781244666 @default.
- W1969409728 hasConcept C2781378642 @default.
- W1969409728 hasConcept C2909621147 @default.
- W1969409728 hasConcept C534529494 @default.
- W1969409728 hasConcept C71924100 @default.
- W1969409728 hasConcept C9418649 @default.
- W1969409728 hasConceptScore W1969409728C126322002 @default.
- W1969409728 hasConceptScore W1969409728C142724271 @default.
- W1969409728 hasConceptScore W1969409728C150489694 @default.
- W1969409728 hasConceptScore W1969409728C2777405647 @default.
- W1969409728 hasConceptScore W1969409728C2777543607 @default.
- W1969409728 hasConceptScore W1969409728C2777714996 @default.
- W1969409728 hasConceptScore W1969409728C2778341716 @default.
- W1969409728 hasConceptScore W1969409728C2778821649 @default.
- W1969409728 hasConceptScore W1969409728C2779412668 @default.
- W1969409728 hasConceptScore W1969409728C2780559512 @default.
- W1969409728 hasConceptScore W1969409728C2781244666 @default.
- W1969409728 hasConceptScore W1969409728C2781378642 @default.
- W1969409728 hasConceptScore W1969409728C2909621147 @default.
- W1969409728 hasConceptScore W1969409728C534529494 @default.
- W1969409728 hasConceptScore W1969409728C71924100 @default.
- W1969409728 hasConceptScore W1969409728C9418649 @default.
- W1969409728 hasIssue "3" @default.
- W1969409728 hasLocation W19694097281 @default.
- W1969409728 hasLocation W19694097282 @default.
- W1969409728 hasOpenAccess W1969409728 @default.
- W1969409728 hasPrimaryLocation W19694097281 @default.
- W1969409728 hasRelatedWork W1658506572 @default.
- W1969409728 hasRelatedWork W1982707513 @default.
- W1969409728 hasRelatedWork W2009907223 @default.
- W1969409728 hasRelatedWork W2033071947 @default.
- W1969409728 hasRelatedWork W2080161784 @default.
- W1969409728 hasRelatedWork W2133994323 @default.
- W1969409728 hasRelatedWork W2472837931 @default.
- W1969409728 hasRelatedWork W2555905101 @default.
- W1969409728 hasRelatedWork W2961150331 @default.
- W1969409728 hasRelatedWork W3032384832 @default.
- W1969409728 hasVolume "41" @default.
- W1969409728 isParatext "false" @default.
- W1969409728 isRetracted "false" @default.
- W1969409728 magId "1969409728" @default.
- W1969409728 workType "article" @default.