Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969432824> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1969432824 endingPage "211" @default.
- W1969432824 startingPage "201" @default.
- W1969432824 abstract "Highly purified synthetic peptides representing portions of the 68–86 sequence of guinea pig (GP) myelin basic protein (GPMBP) were used to define the N- and C-termini of encephalitogenic determinants that cause experimental autimmune encephalomyelitis (EAE) in Lewis rats. Each peptide was tested for: (a) induction of EAE, (b) in vitro potentiation of EAE transfer activity by GPMBP-sensitized lymph node cells (LNC), (c) in vitro proliferation of GPMBP-sensitized LNC, and (d) in vitro proliferation of a GPMBP-reactive line of EAE-inducing T cells. In these bioassays, the general rank order of potency was: GPMBP≥GP68−86≥GP72–86>[G84]GP68−86≥GP68−84⪢GP75−85≥GP75−84 = virtually no activity. These results demonstrate that the encephalitogenic region is bounded by the 72–74 and 84–86 sequences. Further evidence presented herein indicates that the 75–84 sequence contains the primary antigenic features for specific T cell recognition of the encephalitogenic region." @default.
- W1969432824 created "2016-06-24" @default.
- W1969432824 creator A5017340107 @default.
- W1969432824 creator A5023957312 @default.
- W1969432824 creator A5028409625 @default.
- W1969432824 creator A5071082165 @default.
- W1969432824 date "1990-03-01" @default.
- W1969432824 modified "2023-10-10" @default.
- W1969432824 title "The N- and C-terminal boundaries of myelin basic protein determinants required for encephalitogenic and proliferative responses of Lewis rat T cells☆☆☆" @default.
- W1969432824 cites W1500044781 @default.
- W1969432824 cites W1518237933 @default.
- W1969432824 cites W1522354049 @default.
- W1969432824 cites W1542728222 @default.
- W1969432824 cites W1589975312 @default.
- W1969432824 cites W1596914691 @default.
- W1969432824 cites W1619864847 @default.
- W1969432824 cites W1969868626 @default.
- W1969432824 cites W1982024491 @default.
- W1969432824 cites W1999368185 @default.
- W1969432824 cites W2018661507 @default.
- W1969432824 cites W2060263182 @default.
- W1969432824 cites W2061051739 @default.
- W1969432824 cites W2064775272 @default.
- W1969432824 cites W2080160473 @default.
- W1969432824 cites W2085291035 @default.
- W1969432824 cites W2176716563 @default.
- W1969432824 doi "https://doi.org/10.1016/0165-5728(90)90002-5" @default.
- W1969432824 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1689742" @default.
- W1969432824 hasPublicationYear "1990" @default.
- W1969432824 type Work @default.
- W1969432824 sameAs 1969432824 @default.
- W1969432824 citedByCount "19" @default.
- W1969432824 countsByYear W19694328242013 @default.
- W1969432824 countsByYear W19694328242014 @default.
- W1969432824 countsByYear W19694328242017 @default.
- W1969432824 crossrefType "journal-article" @default.
- W1969432824 hasAuthorship W1969432824A5017340107 @default.
- W1969432824 hasAuthorship W1969432824A5023957312 @default.
- W1969432824 hasAuthorship W1969432824A5028409625 @default.
- W1969432824 hasAuthorship W1969432824A5071082165 @default.
- W1969432824 hasConcept C134018914 @default.
- W1969432824 hasConcept C147483822 @default.
- W1969432824 hasConcept C153911025 @default.
- W1969432824 hasConcept C185592680 @default.
- W1969432824 hasConcept C202751555 @default.
- W1969432824 hasConcept C203014093 @default.
- W1969432824 hasConcept C2776090121 @default.
- W1969432824 hasConcept C2777899865 @default.
- W1969432824 hasConcept C2778609137 @default.
- W1969432824 hasConcept C2780640218 @default.
- W1969432824 hasConcept C2780876595 @default.
- W1969432824 hasConcept C529278444 @default.
- W1969432824 hasConcept C55493867 @default.
- W1969432824 hasConcept C86803240 @default.
- W1969432824 hasConcept C8891405 @default.
- W1969432824 hasConceptScore W1969432824C134018914 @default.
- W1969432824 hasConceptScore W1969432824C147483822 @default.
- W1969432824 hasConceptScore W1969432824C153911025 @default.
- W1969432824 hasConceptScore W1969432824C185592680 @default.
- W1969432824 hasConceptScore W1969432824C202751555 @default.
- W1969432824 hasConceptScore W1969432824C203014093 @default.
- W1969432824 hasConceptScore W1969432824C2776090121 @default.
- W1969432824 hasConceptScore W1969432824C2777899865 @default.
- W1969432824 hasConceptScore W1969432824C2778609137 @default.
- W1969432824 hasConceptScore W1969432824C2780640218 @default.
- W1969432824 hasConceptScore W1969432824C2780876595 @default.
- W1969432824 hasConceptScore W1969432824C529278444 @default.
- W1969432824 hasConceptScore W1969432824C55493867 @default.
- W1969432824 hasConceptScore W1969432824C86803240 @default.
- W1969432824 hasConceptScore W1969432824C8891405 @default.
- W1969432824 hasIssue "3" @default.
- W1969432824 hasLocation W19694328241 @default.
- W1969432824 hasLocation W19694328242 @default.
- W1969432824 hasOpenAccess W1969432824 @default.
- W1969432824 hasPrimaryLocation W19694328241 @default.
- W1969432824 hasRelatedWork W1558133685 @default.
- W1969432824 hasRelatedWork W1969554271 @default.
- W1969432824 hasRelatedWork W2012988685 @default.
- W1969432824 hasRelatedWork W2013030002 @default.
- W1969432824 hasRelatedWork W2035718450 @default.
- W1969432824 hasRelatedWork W2060132222 @default.
- W1969432824 hasRelatedWork W2087355971 @default.
- W1969432824 hasRelatedWork W2090613411 @default.
- W1969432824 hasRelatedWork W2377679890 @default.
- W1969432824 hasRelatedWork W318590707 @default.
- W1969432824 hasVolume "26" @default.
- W1969432824 isParatext "false" @default.
- W1969432824 isRetracted "false" @default.
- W1969432824 magId "1969432824" @default.
- W1969432824 workType "article" @default.