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- W1969453889 abstract "Complete sets of chromosome-specific painting probes, derived from flow-sorted chromosomes of human (HSA), <i>Equus caballus</i> (ECA) and <i>Equus burchelli</i> (EBU) were used to delineate conserved chromosomal segments between human and <i>Equus burchelli</i>, and among four equid species, <i>E. przewalskii</i> (EPR), <i>E. caballus, E. burchelli</i> and <i>E. zebra hartmannae</i> (EZH) by cross-species chromosome painting. Genome-wide comparative maps between these species have been established. Twenty-two human autosomal probes revealed 48 conserved segments in <i>E. burchelli</i>. The adjacent segment combinations HSA3/21, 7/16p, 16q/19q, 14/15, 12/22 and 4/8, presumed ancestral syntenies for all eutherian mammals, were also found conserved in <i>E. burchelli</i>. The comparative maps of equids allow for the unequivocal characterization of chromosomal rearrangements that differentiate the karyotypes of these equid species. The karyotypes of <i>E. przewalskii</i> and <i>E. caballus</i> differ by one Robertsonian translocation (ECA5 = EPR23 + EPR24); numerous Robertsonian translocations and tandem fusions and several inversions account for the karyotypic differences between the horses and zebras. Our results shed new light on the karyotypic evolution of Equidae." @default.
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- W1969453889 date "2003-01-01" @default.
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- W1969453889 title "Karyotypic relationships of horses and zebras: results of cross-species chromosome painting" @default.
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- W1969453889 doi "https://doi.org/10.1159/000075755" @default.
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