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• W1969500052 abstract "Computerized spectral analysis of the EEG was performed in 35 patients with Alzheimer's disease and compared to patients with major depression (23) and healthy elderly controls (61). Compared to controls, demented patients had a significant increase in the theta and alpha1 bandwidths as well as an increased theta-beta difference. The parasagittal mean frequency, beta1 and beta2 activity were significantly decreased. Depressed patients differed from demented patients, particularly at the lower end of the spectrum, having significantly less delta and theta activity. Like the demented group, depressed patients also had a decreased parasagittal mean frequency, beta1 and beta2 when compared to controls. In demented patients, there was a high correlation between several spectral parameters (parasagittal mean frequency, delta and theta activity, and the theta-beta difference) and the Folstein score. EEG measures used for discriminant analysis were more accurate in identifying demented patients who had lower Folstein scores. On a effectué l'analyse spectrale par ordinateur des EEG de 35 patients atteints de la maladie d'Alzheimer puis comparé les résultats à ceux de patients atteints de dépression profonde (23) et à ceux de sujets sains âgés témoins (61). Par rapport aux contrôles, les patients déments ont présenté une augmentation significative dans les bandes thêta et alpha1 ainsi qu'une plus grande différence thêta-bêta. La fréquence moyenne parasagittale était significativement diminuée ainsi que l'activité bêta1 et bêta2. Les patients dépressifs se distinguaient de patients déments, en particulier dans la partie basse du spectre, en présentant significativement moins d'activité delta et thêta. Toutefois, comme pour le groupe des déments, les patients dépressifs présentaient, par rapport au témoins, une diminution de leur fréquence moyenne parasagittale, et de leur activité bêta1 et bêta2. Chez les patients déments, plusieurs paramètres du spectre (fréquence moyenne parasagittale, activité delta et thêta, différence thêta-bêta) étaient étroitement corrélés avec le score de Folstein. La discrimination par l'EEG a été plus précise pour identier les patients déments qui présentaient des scores de Folstein faibles." @default.
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• W1969500052 date "1986-12-01" @default.
• W1969500052 modified "2023-10-11" @default.
• W1969500052 title "Computerized EEG spectral analysis in elderly normal, demented and depressed subjects" @default.
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• W1969500052 doi "https://doi.org/10.1016/0013-4694(86)90184-7" @default.
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