FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969562816> ?p ?o ?g. }

• W1969562816 endingPage "807" @default.
• W1969562816 startingPage "800" @default.
• W1969562816 abstract "Background and aims To characterise changes in generation of cellular reactive oxygen species (ROS) in healthy males during the postprandial state, and to analyse the influence of the postprandial state on endothelial ROS generation and endothelial dysfunction. Methods and results Seventeen healthy subjects were recruited. Blood samples were collected in the fasting state and 2, 4, 6 and 8 h after liquid-meal intake (composition: 25% fat, 55% dextromaltose and 14% protein), providing 40 g fat m−2 body surface. Plasma lipids, apolipoproteins, glucose and insulin were measured during this period. Peripheral blood mononuclear cells (PBMCs) were isolated by density-gradient centrifugation. The influence of postprandial state on intracellular ROS generation was measured by two different methods in PBMCs and in a human immortalised endothelial cell line (ECV 304). Artery flow-mediated vasodilation (FMD) was used to evaluate the endothelial function, and oxygen consumption by PBMCs was measured. Reduced ROS generation was observed in all methods and cells during the postprandial period. FMD was impaired 8 h after meal intake (23±6 vs. 13±2, P<0.05 vs. baseline). The consumption of oxygen was reduced in PBMCs (−14% into 2 h, P<0.05 vs. baseline and −27% after 4 h, P<0.01 vs. baseline). ROS generation was correlated with plasma lipids, insulin, apolipoproteins and oxygen consumption. Conclusions In contrast to the previously reported elevation of postprandial oxidative stress, this study shows reduced ROS generation in PBMCs and in ECV 304. Data obtained in both cellular models suggest the existence of a protective response against plasma postprandial oxidative stress." @default.
• W1969562816 created "2016-06-24" @default.
• W1969562816 creator A5009718156 @default.
• W1969562816 creator A5025429579 @default.
• W1969562816 creator A5031060285 @default.
• W1969562816 creator A5048435898 @default.
• W1969562816 creator A5088345070 @default.
• W1969562816 date "2011-10-01" @default.
• W1969562816 modified "2023-10-01" @default.
• W1969562816 title "Reduction in generation of reactive oxygen species and endothelial dysfunction during postprandial state" @default.
• W1969562816 cites W100479555 @default.
• W1969562816 cites W1555489744 @default.
• W1969562816 cites W1944372712 @default.
• W1969562816 cites W1968072950 @default.
• W1969562816 cites W1975936284 @default.
• W1969562816 cites W1976616659 @default.
• W1969562816 cites W1978677861 @default.
• W1969562816 cites W1980018066 @default.
• W1969562816 cites W1988371661 @default.
• W1969562816 cites W1989743926 @default.
• W1969562816 cites W2002926183 @default.
• W1969562816 cites W2011925577 @default.
• W1969562816 cites W2015635582 @default.
• W1969562816 cites W2018048378 @default.
• W1969562816 cites W2028770962 @default.
• W1969562816 cites W2069418862 @default.
• W1969562816 cites W2071958960 @default.
• W1969562816 cites W2072265495 @default.
• W1969562816 cites W2076021360 @default.
• W1969562816 cites W2084539154 @default.
• W1969562816 cites W2108318266 @default.
• W1969562816 cites W2113553969 @default.
• W1969562816 cites W2118310760 @default.
• W1969562816 cites W2122166221 @default.
• W1969562816 cites W2124441017 @default.
• W1969562816 cites W2138415287 @default.
• W1969562816 cites W2148789868 @default.
• W1969562816 cites W2159918504 @default.
• W1969562816 cites W2163289904 @default.
• W1969562816 cites W2324841714 @default.
• W1969562816 cites W2337109902 @default.
• W1969562816 doi "https://doi.org/10.1016/j.numecd.2010.02.010" @default.
• W1969562816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20674308" @default.
• W1969562816 hasPublicationYear "2011" @default.
• W1969562816 type Work @default.
• W1969562816 sameAs 1969562816 @default.
• W1969562816 citedByCount "2" @default.
• W1969562816 countsByYear W19695628162016 @default.
• W1969562816 crossrefType "journal-article" @default.
• W1969562816 hasAuthorship W1969562816A5009718156 @default.
• W1969562816 hasAuthorship W1969562816A5025429579 @default.
• W1969562816 hasAuthorship W1969562816A5031060285 @default.
• W1969562816 hasAuthorship W1969562816A5048435898 @default.
• W1969562816 hasAuthorship W1969562816A5088345070 @default.
• W1969562816 hasConcept C126322002 @default.
• W1969562816 hasConcept C134018914 @default.
• W1969562816 hasConcept C137061746 @default.
• W1969562816 hasConcept C185592680 @default.
• W1969562816 hasConcept C202751555 @default.
• W1969562816 hasConcept C2776151105 @default.
• W1969562816 hasConcept C2778163477 @default.
• W1969562816 hasConcept C2778199505 @default.
• W1969562816 hasConcept C2779306644 @default.
• W1969562816 hasConcept C2780972559 @default.
• W1969562816 hasConcept C48349386 @default.
• W1969562816 hasConcept C55493867 @default.
• W1969562816 hasConcept C71924100 @default.
• W1969562816 hasConceptScore W1969562816C126322002 @default.
• W1969562816 hasConceptScore W1969562816C134018914 @default.
• W1969562816 hasConceptScore W1969562816C137061746 @default.
• W1969562816 hasConceptScore W1969562816C185592680 @default.
• W1969562816 hasConceptScore W1969562816C202751555 @default.
• W1969562816 hasConceptScore W1969562816C2776151105 @default.
• W1969562816 hasConceptScore W1969562816C2778163477 @default.
• W1969562816 hasConceptScore W1969562816C2778199505 @default.
• W1969562816 hasConceptScore W1969562816C2779306644 @default.
• W1969562816 hasConceptScore W1969562816C2780972559 @default.
• W1969562816 hasConceptScore W1969562816C48349386 @default.
• W1969562816 hasConceptScore W1969562816C55493867 @default.
• W1969562816 hasConceptScore W1969562816C71924100 @default.
• W1969562816 hasIssue "10" @default.
• W1969562816 hasLocation W19695628161 @default.
• W1969562816 hasLocation W19695628162 @default.
• W1969562816 hasOpenAccess W1969562816 @default.
• W1969562816 hasPrimaryLocation W19695628161 @default.
• W1969562816 hasRelatedWork W2045145511 @default.
• W1969562816 hasRelatedWork W2064185418 @default.
• W1969562816 hasRelatedWork W2080135029 @default.
• W1969562816 hasRelatedWork W2089449544 @default.
• W1969562816 hasRelatedWork W2129737421 @default.
• W1969562816 hasRelatedWork W2153745306 @default.
• W1969562816 hasRelatedWork W2159000141 @default.
• W1969562816 hasRelatedWork W2594630750 @default.
• W1969562816 hasRelatedWork W2748952813 @default.
• W1969562816 hasRelatedWork W2758620209 @default.
• W1969562816 hasVolume "21" @default.
• W1969562816 isParatext "false" @default.
• W1969562816 isRetracted "false" @default.

• next