Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969577067> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W1969577067 endingPage "337" @default.
- W1969577067 startingPage "332" @default.
- W1969577067 abstract "To investigate the accumulation of highly phosphorylated guanosine nucleotides in Staphylococcus aureus 8325-4 following nutrient deprivation.Nutrient shiftdown of Staph. aureus, HPLC of nucleotides and Western blotting of cell-free extracts. ppGpp rapidly accumulated when cells were deprived of isoleucine following addition of mupirocin, or after carbon deprivation. In contrast, total amino acid starvation led to delayed production of ppGp, which suggests that Staph. aureus exhibits a unique response to total amino acid deprivation compared with other eubacteria. Intracellular ppGp was observed at high levels under all starvation conditions, which suggests that this nucleotide is linked to nutrient limitation and may therefore be involved in regulating the stringent response in Staph. aureus. pppGpp was not observed under any nutrient-limiting condition. Western blot analysis of whole-cell extracts from Staph. aureus 8325-4, showed that antibodies to RelA and SpoT cross-reacted under conditions that detected these proteins in Escherichia coli.Staph. aureus produces ppGpp and ppGp following nutrient limitation. Immunological analysis indicates that Staph. aureus contains RelA and SpoT proteins, similar to those produced by E. coli.This study provides a new example of the diversity of metabolic regulations in bacteria." @default.
- W1969577067 created "2016-06-24" @default.
- W1969577067 creator A5004207304 @default.
- W1969577067 creator A5017814917 @default.
- W1969577067 creator A5070222031 @default.
- W1969577067 date "2000-10-01" @default.
- W1969577067 modified "2023-10-18" @default.
- W1969577067 title "Accumulation of ppGpp and ppGp in Staphylococcus aureus 8325-4 following nutrient starvation" @default.
- W1969577067 cites W1481887030 @default.
- W1969577067 cites W1484445362 @default.
- W1969577067 cites W1491057997 @default.
- W1969577067 cites W1539961590 @default.
- W1969577067 cites W1616230851 @default.
- W1969577067 cites W1939622630 @default.
- W1969577067 cites W1989074746 @default.
- W1969577067 cites W2013725703 @default.
- W1969577067 cites W2056426580 @default.
- W1969577067 cites W2070108182 @default.
- W1969577067 cites W2072015109 @default.
- W1969577067 cites W2106681306 @default.
- W1969577067 cites W2113481566 @default.
- W1969577067 cites W2129714441 @default.
- W1969577067 cites W216486140 @default.
- W1969577067 cites W225100202 @default.
- W1969577067 cites W2342497210 @default.
- W1969577067 cites W4235938473 @default.
- W1969577067 doi "https://doi.org/10.1046/j.1472-765x.2000.00822.x" @default.
- W1969577067 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11068918" @default.
- W1969577067 hasPublicationYear "2000" @default.
- W1969577067 type Work @default.
- W1969577067 sameAs 1969577067 @default.
- W1969577067 citedByCount "39" @default.
- W1969577067 countsByYear W19695770672012 @default.
- W1969577067 countsByYear W19695770672013 @default.
- W1969577067 countsByYear W19695770672014 @default.
- W1969577067 countsByYear W19695770672015 @default.
- W1969577067 countsByYear W19695770672016 @default.
- W1969577067 countsByYear W19695770672019 @default.
- W1969577067 countsByYear W19695770672020 @default.
- W1969577067 countsByYear W19695770672021 @default.
- W1969577067 countsByYear W19695770672022 @default.
- W1969577067 crossrefType "journal-article" @default.
- W1969577067 hasAuthorship W1969577067A5004207304 @default.
- W1969577067 hasAuthorship W1969577067A5017814917 @default.
- W1969577067 hasAuthorship W1969577067A5070222031 @default.
- W1969577067 hasConcept C104317684 @default.
- W1969577067 hasConcept C26628138 @default.
- W1969577067 hasConcept C2777995097 @default.
- W1969577067 hasConcept C2779489039 @default.
- W1969577067 hasConcept C512185932 @default.
- W1969577067 hasConcept C515207424 @default.
- W1969577067 hasConcept C523546767 @default.
- W1969577067 hasConcept C54355233 @default.
- W1969577067 hasConcept C547475151 @default.
- W1969577067 hasConcept C55493867 @default.
- W1969577067 hasConcept C86803240 @default.
- W1969577067 hasConcept C89423630 @default.
- W1969577067 hasConceptScore W1969577067C104317684 @default.
- W1969577067 hasConceptScore W1969577067C26628138 @default.
- W1969577067 hasConceptScore W1969577067C2777995097 @default.
- W1969577067 hasConceptScore W1969577067C2779489039 @default.
- W1969577067 hasConceptScore W1969577067C512185932 @default.
- W1969577067 hasConceptScore W1969577067C515207424 @default.
- W1969577067 hasConceptScore W1969577067C523546767 @default.
- W1969577067 hasConceptScore W1969577067C54355233 @default.
- W1969577067 hasConceptScore W1969577067C547475151 @default.
- W1969577067 hasConceptScore W1969577067C55493867 @default.
- W1969577067 hasConceptScore W1969577067C86803240 @default.
- W1969577067 hasConceptScore W1969577067C89423630 @default.
- W1969577067 hasIssue "4" @default.
- W1969577067 hasLocation W19695770671 @default.
- W1969577067 hasLocation W19695770672 @default.
- W1969577067 hasOpenAccess W1969577067 @default.
- W1969577067 hasPrimaryLocation W19695770671 @default.
- W1969577067 hasRelatedWork W1485780383 @default.
- W1969577067 hasRelatedWork W2029581770 @default.
- W1969577067 hasRelatedWork W2036347073 @default.
- W1969577067 hasRelatedWork W2042446299 @default.
- W1969577067 hasRelatedWork W2313387403 @default.
- W1969577067 hasRelatedWork W2383245328 @default.
- W1969577067 hasRelatedWork W2900947121 @default.
- W1969577067 hasRelatedWork W3094022890 @default.
- W1969577067 hasRelatedWork W3108873220 @default.
- W1969577067 hasRelatedWork W3109929327 @default.
- W1969577067 hasVolume "31" @default.
- W1969577067 isParatext "false" @default.
- W1969577067 isRetracted "false" @default.
- W1969577067 magId "1969577067" @default.
- W1969577067 workType "article" @default.