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- W1969579898 abstract "Sunil Sazawal and colleagues did a large randomised controlled trial of zinc supplementation in a malaria holoendemic area of east Africa which showed no significant effect on mortality among children younger than 5 years. However in subgroup analyses Sazawal and colleagues showed a significant effect of the intervention on mortality in children older than 12 months and this effect was significant for boys (relative risk 0.71) but not for girls (0.95). We did a similar study on the effects of zinc supplementation in a malaria holoendemic area of west Africa. Here zinc supplementation had no effect on malaria morbidity but significantly reduced diarrhoea morbidity in children younger than 3 years. A subgroup analysis showed that this effect was also significant for boys (relative risk 0.67) but not for girls (1.03) a finding that needs further explanation. Finally we showed a significant association between malnutrition and mortality but not between malnutrition and malaria in this cohort. (excerpt)" @default.
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- W1969579898 date "2007-06-01" @default.
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- W1969579898 title "Malnutrition, zinc deficiency, and malaria in Africa" @default.
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- W1969579898 doi "https://doi.org/10.1016/s0140-6736(07)61001-0" @default.
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