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- W1969596645 abstract "<h3>To the Editor:—</h3> Recent publicity (<b>196</b>, June 13, 1966, adv p 25;<b>197</b>: 592 [Aug 17] 1966; and<i>AMA News</i>Oct 17, 1966, p 4) emphasized the mystery surrounding unexplained myocarditis, heart failure, and death in heavy beer drinkers. Perhaps the mystery can be explained by vitamin B<sub>6</sub>deficiency rather than by some possible toxin such as cobaltous additives. French reported that myocardial necrosis was frequent in vitamin B<sub>6</sub>-deficient rats.<sup>1</sup>Assada and Mitsumori have shown a decrease in production of serum pyridoxal phosphate (the active biological form of vitamin B<sub>6</sub>) in humans who have liver disease.<sup>2</sup>Perhaps the heavy beer drinkers were alcoholics who were unable to manufacture sufficient pyridoxal phosphate because of vitamin B<sub>6</sub>deficiency and liver damage." @default.
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- W1969596645 date "1966-12-19" @default.
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- W1969596645 title "Vitamin B6 Deficiency In Beer Drinkers" @default.
- W1969596645 doi "https://doi.org/10.1001/jama.1966.03110250128043" @default.
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