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- W1969606723 abstract "To evaluate changes in the cardiac preload of monochorionic twins with twin-to-twin transfusion syndrome (TTTS), before and after laser coagulation of the communicating anastomosis (LPCA). A total of 22 pairs of monochorionic twin pregnancies affected with TTTS were evaluated. According to the Quintero staging system for severity, 12 were classified in stage I, 10 in stage II, 5 in stage III and 5 in stage IV. All were subjected to LPCA. Preload index in the inferior vena cava (IVCPLI), pulsatility index in the ductus venosus (DVPI) and tricuspid E/A waveform relationship (Tric E/A) were calculated with pulsed Doppler ultrasound in both twins one day before LPCA and 3 and 7 days later. Changes over time for recipient and donor twins and the differences between them were estimated and evaluated by analysis of variance (ANOVA). At the end of the studied period, the obtained values were compared with a control group of dichorionic twins at the same gestational age. Before LPCA, the recipient fetuses showed an increased DVPI and IVCPLI as compared with the donors. In contrast, 3 days after LPCA, the donor twins showed a higher DV PI and IVC PLI than the recipients. Seven days later, there were no differences between both. There were no differences in the Tric E/A but the same trend over time as the IVC and DV was observed. According to the Quintero grading system, all fetuses showed the same trend as described, however, only cases in stages III and IV showed significant differences. Seven days after LPCA; DVPI, IVCPLI and Tric E/A from monochorionic twin pregnancies were still higher than control dichorionic twins. After LPCA the donor twin transiently increases, and the recipient twin progressively decreases its preload cardiac volume. This adaptive response in the donor may explain post-laer transient hydropic signs occurring in part of these fetuses." @default.
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- W1969606723 date "2004-08-01" @default.
- W1969606723 modified "2023-09-27" @default.
- W1969606723 title "P12.30: Fetal cardiac preload changes in twin-to-twin transfusion syndrome after fetoscopic laser coagulation of the placental anastomosis" @default.
- W1969606723 doi "https://doi.org/10.1002/uog.1578" @default.
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