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- W1969608497 abstract "The association of endocrine gland adenomata and peptic ulceration has been recognized for some time. Zollinger and Ellison in 19551described a syndrome consisting of multiple recurrent peptic ulcerations, gastric hypersecretion, and non-beta islet cell tumor of the pancreas. Subsequently, these and other authors have delineated this syndrome further.2-7 The present review of 86 documented cases of the Zollinger-Ellison syndrome2,3,6-57was prompted by, and includes, a recent case of our own57in which unusual features provide evidence for the theory of extrapancreatic stimulation as an etiologic factor in the Zollinger-Ellison syndrome. Although this syndrome has received much attention, the diagnosis was suspected preoperatively in only 22% of the case reports reviewed and the mortality rate was 54%. Because of the grave prognosis and the infrequency with which diagnosis is made on clinical grounds, this report is compiled to define the syndrome by analyzing the reviewed cases" @default.
- W1969608497 created "2016-06-24" @default.
- W1969608497 creator A5014291760 @default.
- W1969608497 date "1964-09-01" @default.
- W1969608497 modified "2023-10-04" @default.
- W1969608497 title "Zollinger-Ellison Syndrome" @default.
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- W1969608497 doi "https://doi.org/10.1001/archinte.1964.03860090115012" @default.
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