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- W1969668636 abstract "To investigate the origin of the fast oscillation, a phenomenon in the electroretinogram evoked with stimulus frequencies of about 8 mHz (a period time of about 2 min), we recorded responses from retina and pigment epithelium in the macaque. Micropipettes were placed in the subretinal space and in the vitreous close to the retina; the reference electrode was in the orbit behind the eye. Thus, simultaneous recordings were obtained of the trans-epithelial, the trans-retinal and the trans-tissue (vitreal) potential. At 10 mHz the trans-retinal and the trans-epithelial responses are of about equal magnitude but of opposite phase, resulting in a small and rather variable vitreal potential. The origin of the fast oscillation evoked with repetitive stimuli lies in subtle differences between retinal and pigment epithelial potentials, in which a pigment epithelial event plays an important role. For single stimuli lasting 60 s again the trans-epithelial and trans-retinal responses were of equal magnitude and opposite polarity. The epithelial responses were found to return more quickly towards the baseline than the retinal responses. In vitreal recordings this causes a trough between the c-wave and the light peak which is referred to as the trough fast oscillation. Most of the trough fast oscillation is caused by a pigment epithelial event. In view of the complexity of the fast oscillation evoked with repetitive stimuli it might be difficult to relate pathology to specific neuro-epithelial structures." @default.
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- W1969668636 date "1986-01-01" @default.
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- W1969668636 title "Origin of the fast oscillation in the electroretinogram of the macaque" @default.
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- W1969668636 doi "https://doi.org/10.1016/0042-6989(86)90005-2" @default.
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