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- W1969709780 abstract "A large amount of nitric oxide (NO) production following the induction of inducible NO synthase (iNOS) gene has been implicated in the pathogenesis of inflammatory diseases. A phenolic compound, bakuchiol, isolated from Psoralea corylifolia L. (Leguminosae) inhibited NO production in RAW 264.7 macrophages activated with interferon-γ and lipopolysaccharide. The mechanistic studies showed that bakuchiol inhibited the expression of iNOS mRNA through the inactivation of nuclear transcription factor-κB. Thus, bakuchiol may be a useful candidate for the development of a drug to treat inflammatory diseases related to iNOS gene over-expression." @default.
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- W1969709780 date "2001-09-01" @default.
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- W1969709780 title "Bakuchiol from Psoralea corylifolia inhibits the expression of inducible nitric oxide synthase gene via the inactivation of nuclear transcription factor-κB in RAW 264.7 macrophages" @default.
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- W1969709780 doi "https://doi.org/10.1016/s1567-5769(01)00110-2" @default.
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