Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969731392> ?p ?o ?g. }
- W1969731392 endingPage "393" @default.
- W1969731392 startingPage "388" @default.
- W1969731392 abstract "We tested the hypothesis in a rat model that body cooling suppresses circulatory shock and cerebral ischemia in heatstroke. Animals under urethane anesthesia were exposed to water blanket temperature (Tblanket) of 42 degrees C until mean arterial pressure (MAP) and local cerebral blood flow (CBF) in the hippocampus began to decrease from their peak levels, which was arbitrarily defined as the onset of heatstroke. Control rats were exposed to 26 degrees C. Extracellular concentrations of glutamate, glycerol, lactate, and lactate/pyruvate in the hippocampus were assessed by microdialysis methods. Cooling was accomplished by decreasing Tblanket from 42 degrees C to 16 degrees C. The values of MAP and CBF after the onset of heat stroke in heatstroke rats received no cooling were all significantly lower than those in control rats. However, the neuronal damage score and extracellular levels of ischemia and damage markers in the hippocampus were greater. Cooling immediately after the onset of heatstroke reduced the heatstroke-induced circulatory shock, cerebral ischemia, neuronal damage, and surge of tissue ischemia and damage markers in the hippocampus, and resulted in prolongation of survival time. Delaying the onset of cooling reduced the therapeutic efficiency. The results suggest that body cooling attenuates circulatory shock and cerebral ischemia insults in heatstroke." @default.
- W1969731392 created "2016-06-24" @default.
- W1969731392 creator A5002184470 @default.
- W1969731392 creator A5025473541 @default.
- W1969731392 creator A5076975699 @default.
- W1969731392 creator A5083830540 @default.
- W1969731392 date "2003-04-01" @default.
- W1969731392 modified "2023-09-23" @default.
- W1969731392 title "Hypothermia Attenuates Circulatory Shock and Cerebral Ischemia in Experimental Heatstroke" @default.
- W1969731392 cites W1762408770 @default.
- W1969731392 cites W1893731892 @default.
- W1969731392 cites W1969907992 @default.
- W1969731392 cites W1970552378 @default.
- W1969731392 cites W1970881569 @default.
- W1969731392 cites W1972775765 @default.
- W1969731392 cites W1973406593 @default.
- W1969731392 cites W1973587217 @default.
- W1969731392 cites W1976554975 @default.
- W1969731392 cites W1982892406 @default.
- W1969731392 cites W1989386811 @default.
- W1969731392 cites W1989539304 @default.
- W1969731392 cites W1991022487 @default.
- W1969731392 cites W1994433195 @default.
- W1969731392 cites W1998123810 @default.
- W1969731392 cites W2000470437 @default.
- W1969731392 cites W2006867062 @default.
- W1969731392 cites W2025513151 @default.
- W1969731392 cites W2027337089 @default.
- W1969731392 cites W2031298646 @default.
- W1969731392 cites W2053557803 @default.
- W1969731392 cites W2055584145 @default.
- W1969731392 cites W2065920545 @default.
- W1969731392 cites W2067581607 @default.
- W1969731392 cites W2070139095 @default.
- W1969731392 cites W2071665004 @default.
- W1969731392 cites W2079132260 @default.
- W1969731392 cites W2081849695 @default.
- W1969731392 cites W2103722437 @default.
- W1969731392 cites W2104012222 @default.
- W1969731392 cites W2130614261 @default.
- W1969731392 cites W2131150967 @default.
- W1969731392 cites W2204738624 @default.
- W1969731392 cites W2277492845 @default.
- W1969731392 cites W2342561698 @default.
- W1969731392 cites W2407095647 @default.
- W1969731392 cites W4240578390 @default.
- W1969731392 doi "https://doi.org/10.1097/00024382-200304000-00016" @default.
- W1969731392 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12688553" @default.
- W1969731392 hasPublicationYear "2003" @default.
- W1969731392 type Work @default.
- W1969731392 sameAs 1969731392 @default.
- W1969731392 citedByCount "68" @default.
- W1969731392 countsByYear W19697313922012 @default.
- W1969731392 countsByYear W19697313922013 @default.
- W1969731392 countsByYear W19697313922014 @default.
- W1969731392 countsByYear W19697313922015 @default.
- W1969731392 countsByYear W19697313922020 @default.
- W1969731392 countsByYear W19697313922021 @default.
- W1969731392 countsByYear W19697313922022 @default.
- W1969731392 countsByYear W19697313922023 @default.
- W1969731392 crossrefType "journal-article" @default.
- W1969731392 hasAuthorship W1969731392A5002184470 @default.
- W1969731392 hasAuthorship W1969731392A5025473541 @default.
- W1969731392 hasAuthorship W1969731392A5076975699 @default.
- W1969731392 hasAuthorship W1969731392A5083830540 @default.
- W1969731392 hasBestOaLocation W19697313921 @default.
- W1969731392 hasConcept C126322002 @default.
- W1969731392 hasConcept C157767197 @default.
- W1969731392 hasConcept C2776153327 @default.
- W1969731392 hasConcept C2777390192 @default.
- W1969731392 hasConcept C2779949491 @default.
- W1969731392 hasConcept C2781161787 @default.
- W1969731392 hasConcept C2781300812 @default.
- W1969731392 hasConcept C2781458332 @default.
- W1969731392 hasConcept C42219234 @default.
- W1969731392 hasConcept C50156730 @default.
- W1969731392 hasConcept C529278444 @default.
- W1969731392 hasConcept C541997718 @default.
- W1969731392 hasConcept C71924100 @default.
- W1969731392 hasConcept C72859922 @default.
- W1969731392 hasConceptScore W1969731392C126322002 @default.
- W1969731392 hasConceptScore W1969731392C157767197 @default.
- W1969731392 hasConceptScore W1969731392C2776153327 @default.
- W1969731392 hasConceptScore W1969731392C2777390192 @default.
- W1969731392 hasConceptScore W1969731392C2779949491 @default.
- W1969731392 hasConceptScore W1969731392C2781161787 @default.
- W1969731392 hasConceptScore W1969731392C2781300812 @default.
- W1969731392 hasConceptScore W1969731392C2781458332 @default.
- W1969731392 hasConceptScore W1969731392C42219234 @default.
- W1969731392 hasConceptScore W1969731392C50156730 @default.
- W1969731392 hasConceptScore W1969731392C529278444 @default.
- W1969731392 hasConceptScore W1969731392C541997718 @default.
- W1969731392 hasConceptScore W1969731392C71924100 @default.
- W1969731392 hasConceptScore W1969731392C72859922 @default.
- W1969731392 hasIssue "4" @default.
- W1969731392 hasLocation W19697313921 @default.
- W1969731392 hasLocation W19697313922 @default.
- W1969731392 hasLocation W19697313923 @default.