Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969738937> ?p ?o ?g. }
- W1969738937 endingPage "248" @default.
- W1969738937 startingPage "244" @default.
- W1969738937 abstract "Although primary angioplasty achieves Thrombolysis In Myocardial Infarction (TIMI) 3 flow in most patients with ST-elevation myocardial infarction, epicardial recanalization does not guarantee optimal perfusion in a large proportion of patients. Multivessel disease has been demonstrated to be associated with impaired survival, however its impact on infarct size has not been largely investigated, that therefore is the aim of the current study.Our population is represented by 827 STEMI patients undergoing primary PCI. Infarct size was evaluated at 30 days by technetium-99m-sestamibi.Multivessel disease was observed in 343 patients (41.5%). It was associated with older age (65 [57-74] vs 63 [53-71], p < 0.001), higher rate of previous MI (6.4% vs 2.5%, p = 0.005), longer ischemia time evaluated as continuous variable (210 [155-280] min vs 196 [145-270] min, p = 0.065) or percentage of patients with ischemia time >3 h (63.7% vs 56.4%, p = 0.038), and a trend in more cardiogenic shock (5.5% vs 2.9%, p = 0.055). Patients with multivessel disease received more often Abciximab (92.1% vs 88.4%, p < 0.001), Intra-aortic balloon pump (6.4% vs 1.9%, p < 0.001). No differences were observed in other clinical or angiographic characteristics. In particular, multivessel disease did not affect the rate of postprocedural TIMI 3 flow (90.9% vs 93.4%, p = 0.18) and ST-segment resolution (52.4% vs 54.9%, p = 0.48). Multivessel disease did not affect infarct size (12.7% [4.5%-24.9%] vs 12.3% [4%-24.1%], p = 0.58). Similar results were observed in subanalyses without any significant interaction for each variable (anterior infarct location (p int = 0.23), gender (p int = 0.9), age (p int = 0.7), diabetes (p int = 0.15)). The absence of any impact of multivessel disease on infarct size was confirmed when the analysis was conducted according to the percentage of patients with infarct size above the median, even after correction for baseline characteristics, such as age, previous MI, ischemia time, use of Gp IIb-IIIa inhibitors, cardiogenic shock, ischemia time (OR [95% CI] = 1.09 [0.82-1.45], p = 0.58).This study shows that among STEMI patients undergoing primary PCI multivessel disease does not affect infarct size." @default.
- W1969738937 created "2016-06-24" @default.
- W1969738937 creator A5004032203 @default.
- W1969738937 creator A5044940459 @default.
- W1969738937 creator A5060506721 @default.
- W1969738937 creator A5062612063 @default.
- W1969738937 creator A5064670948 @default.
- W1969738937 creator A5074401377 @default.
- W1969738937 creator A5077517566 @default.
- W1969738937 creator A5079016321 @default.
- W1969738937 creator A5085268431 @default.
- W1969738937 date "2014-05-01" @default.
- W1969738937 modified "2023-09-27" @default.
- W1969738937 title "Impact of multivessel disease on infarct size among STEMI patients undergoing primary angioplasty" @default.
- W1969738937 cites W154773941 @default.
- W1969738937 cites W1977423202 @default.
- W1969738937 cites W1979949191 @default.
- W1969738937 cites W1993621677 @default.
- W1969738937 cites W1993866437 @default.
- W1969738937 cites W2003144159 @default.
- W1969738937 cites W2004469230 @default.
- W1969738937 cites W2005449065 @default.
- W1969738937 cites W2011498879 @default.
- W1969738937 cites W2015367522 @default.
- W1969738937 cites W2020099275 @default.
- W1969738937 cites W2023266656 @default.
- W1969738937 cites W2031944010 @default.
- W1969738937 cites W2032167693 @default.
- W1969738937 cites W2043385922 @default.
- W1969738937 cites W2050426293 @default.
- W1969738937 cites W2056792656 @default.
- W1969738937 cites W2059517713 @default.
- W1969738937 cites W2059918238 @default.
- W1969738937 cites W2064195086 @default.
- W1969738937 cites W2067224489 @default.
- W1969738937 cites W2073146905 @default.
- W1969738937 cites W2078903829 @default.
- W1969738937 cites W2080898712 @default.
- W1969738937 cites W2081952076 @default.
- W1969738937 cites W2092713997 @default.
- W1969738937 cites W2092724094 @default.
- W1969738937 cites W2093392020 @default.
- W1969738937 cites W2103395291 @default.
- W1969738937 cites W2106605198 @default.
- W1969738937 cites W2129029296 @default.
- W1969738937 cites W2132861593 @default.
- W1969738937 cites W2141604880 @default.
- W1969738937 cites W2149035425 @default.
- W1969738937 cites W2149916913 @default.
- W1969738937 cites W2154173315 @default.
- W1969738937 cites W2319032954 @default.
- W1969738937 cites W462700 @default.
- W1969738937 doi "https://doi.org/10.1016/j.atherosclerosis.2014.02.031" @default.
- W1969738937 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24685816" @default.
- W1969738937 hasPublicationYear "2014" @default.
- W1969738937 type Work @default.
- W1969738937 sameAs 1969738937 @default.
- W1969738937 citedByCount "5" @default.
- W1969738937 countsByYear W19697389372015 @default.
- W1969738937 countsByYear W19697389372017 @default.
- W1969738937 countsByYear W19697389372019 @default.
- W1969738937 countsByYear W19697389372020 @default.
- W1969738937 crossrefType "journal-article" @default.
- W1969738937 hasAuthorship W1969738937A5004032203 @default.
- W1969738937 hasAuthorship W1969738937A5044940459 @default.
- W1969738937 hasAuthorship W1969738937A5060506721 @default.
- W1969738937 hasAuthorship W1969738937A5062612063 @default.
- W1969738937 hasAuthorship W1969738937A5064670948 @default.
- W1969738937 hasAuthorship W1969738937A5074401377 @default.
- W1969738937 hasAuthorship W1969738937A5077517566 @default.
- W1969738937 hasAuthorship W1969738937A5079016321 @default.
- W1969738937 hasAuthorship W1969738937A5085268431 @default.
- W1969738937 hasBestOaLocation W19697389372 @default.
- W1969738937 hasConcept C126322002 @default.
- W1969738937 hasConcept C164705383 @default.
- W1969738937 hasConcept C2776850375 @default.
- W1969738937 hasConcept C2777871224 @default.
- W1969738937 hasConcept C2777995511 @default.
- W1969738937 hasConcept C2779581417 @default.
- W1969738937 hasConcept C2780326628 @default.
- W1969738937 hasConcept C2908647359 @default.
- W1969738937 hasConcept C45393284 @default.
- W1969738937 hasConcept C500558357 @default.
- W1969738937 hasConcept C71924100 @default.
- W1969738937 hasConcept C99454951 @default.
- W1969738937 hasConceptScore W1969738937C126322002 @default.
- W1969738937 hasConceptScore W1969738937C164705383 @default.
- W1969738937 hasConceptScore W1969738937C2776850375 @default.
- W1969738937 hasConceptScore W1969738937C2777871224 @default.
- W1969738937 hasConceptScore W1969738937C2777995511 @default.
- W1969738937 hasConceptScore W1969738937C2779581417 @default.
- W1969738937 hasConceptScore W1969738937C2780326628 @default.
- W1969738937 hasConceptScore W1969738937C2908647359 @default.
- W1969738937 hasConceptScore W1969738937C45393284 @default.
- W1969738937 hasConceptScore W1969738937C500558357 @default.
- W1969738937 hasConceptScore W1969738937C71924100 @default.
- W1969738937 hasConceptScore W1969738937C99454951 @default.
- W1969738937 hasIssue "1" @default.