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- W1969772511 abstract "We previously showed that soluble nitroxides (nitric oxide analogues) mimicked the well-established ability of nitric oxide to cause biofilm dispersal and further showed that these compounds could prevent biofilm formation. Here, we investigated the effect of the nitroxide carboxy-TEMPO in combination with sub μg/ml concentrations of ciprofloxacin on pre-formed flow cell biofilms formed by Gram-negative bacteria. Combination therapy led to substantial eradication of existing biofilms formed by Pseudomonas aeruginosa PA14 (99.3%) and Escherichia coli O157 (93%)." @default.
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- W1969772511 date "2015-02-03" @default.
- W1969772511 modified "2023-10-03" @default.
- W1969772511 title "Potentiation of ciprofloxacin action against Gram-negative bacterial biofilms by a nitroxide" @default.
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- W1969772511 doi "https://doi.org/10.1093/femspd/ftv016" @default.
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