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- W1969795802 endingPage "872" @default.
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- W1969795802 abstract "The neurotoxin α-bungarotoxin (BuTX) has been extensively used as a specific and irreversible ligand to study the nicotinic acetylcholine receptor (nAChR) in skeletal muscle and electric fish. More recently it has been utilized to investigate the possibility of nAChRs in the CNS. The BuTX binding sites in the CNS have biochemical properties similar to muscle, have a distribution similar to other cholinergic markers, and have been histologically demonstrated to bind to post-synaptic membranes. But studies of ganglionic neurons, cultured sympathetic ganglion cells, and the PC 12 cell culture line have raised questions regarding the use of BuTX as a nicotinic receptor ligand in the CNS. The evidence for and against BuTX as a nicotinic receptor ligand is reviewed and discussed." @default.
- W1969795802 created "2016-06-24" @default.
- W1969795802 creator A5006945247 @default.
- W1969795802 creator A5058004540 @default.
- W1969795802 creator A5080955536 @default.
- W1969795802 date "1979-03-01" @default.
- W1969795802 modified "2023-10-12" @default.
- W1969795802 title "α-Bungarotoxin binding sites in the CNS" @default.
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- W1969795802 doi "https://doi.org/10.1016/0024-3205(79)90335-7" @default.
- W1969795802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/376997" @default.
- W1969795802 hasPublicationYear "1979" @default.
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