FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969803280> ?p ?o ?g. }

• W1969803280 endingPage "15" @default.
• W1969803280 startingPage "15" @default.
• W1969803280 abstract "Triclosan (TCS) is a broad-spectrum antimicrobial used in consumer products including toothpaste and hand soap. After being used, TCS is washed or rinsed off and residuals that are not biodegraded or otherwise removed during wastewater treatment can enter the aquatic environment in wastewater effluents and sludges. The environmental exposure and toxicity of TCS has been the subject of various scientific and regulatory discussions in recent years. There have been a number of publications in the past 5 y reporting toxicity, fate and transport, and in-stream monitoring data as well as predictions from aquatic risk assessments. State-of-the-science probabilistic exposure models, including Geography-referenced Regional Exposure Assessment Tool for European Rivers (GREAT-ER) for European surface waters and Pharmaceutical Assessment and Transport Evalutation (PhATE) for US surface waters, have been used to predict in-stream concentrations (PECs). These models take into account spatial and temporal variability in river flows and wastewater emissions based on empirically derived estimates of chemical removal in wastewater treatment and in receiving waters. These model simulations (based on realistic use levels of TCS) have been validated with river monitoring data in areas known to be receiving high wastewater loads. The results suggest that 90th percentile (low flow) TCS concentrations are less than 200 ng/L for the Aire-Calder catchment in the United Kingdom and between 250 ng/L (with in-stream removal) and 850 ng/L (without in-stream removal) for a range of US surface waters. To better identify the aquatic risk of TCS, a species sensitivity distribution (SSD) was constructed based on chronic toxicity values, either no observed effect concentrations (NOECs) or various percentile adverse effect concentrations (EC10-25 values) for 14 aquatic species including fish, invertebrates, macrophytes, and algae. The SSD approach is believed to represent a more realistic threshold of effect than a predicted no effect concentration (PNEC) based on the data from the single most sensitive species tested. The log-logistic SSD was used to estimate a PNEC, based on an HC5,50 (the concentration estimated to affect the survival, reproduction and/or growth of 5% of species with a 50% confidence interval). The PNEC for TCS was 1,550 ng/L. Comparing the SSD-based PNEC with the PECs derived from GREATER and PhATE modeling to simulate in-river conditions in Europe and the United States, the PEC to PNEC ratios are less than unity suggesting risks to pelagic species are low even under the highest likely exposures which would occur immediately downstream of wastewater treatment plant (WWTP) discharge points. In-stream sorption, biodegradation, and photodegradation will further reduce pelagic exposures of TCS. Monitoring data in Europe and the United States corroborate the modeled PEC estimates and reductions in TCS concentrations with distance downstream of WWTP discharges. Environmental metabolites, bioaccumulation, biochemical responses including endocrine-related effects, and community level effects are far less well studied for this chemical but are addressed in the discussion. The aquatic risk assessment for TCS should be refined as additional information becomes available." @default.
• W1969803280 created "2016-06-24" @default.
• W1969803280 creator A5000719992 @default.
• W1969803280 creator A5025805362 @default.
• W1969803280 creator A5037316649 @default.
• W1969803280 creator A5060387940 @default.
• W1969803280 creator A5080235603 @default.
• W1969803280 creator A5086719361 @default.
• W1969803280 creator A5088801421 @default.
• W1969803280 creator A5091603615 @default.
• W1969803280 date "2008-01-01" @default.
• W1969803280 modified "2023-10-01" @default.
• W1969803280 title "Consideration of Exposure and Species Sensitivity of Triclosan in the Freshwater Environment" @default.
• W1969803280 cites W1183739755 @default.
• W1969803280 cites W1525319863 @default.
• W1969803280 cites W1738907399 @default.
• W1969803280 cites W1963942552 @default.
• W1969803280 cites W1984097165 @default.
• W1969803280 cites W1992158459 @default.
• W1969803280 cites W1993633251 @default.
• W1969803280 cites W1996464902 @default.
• W1969803280 cites W2000263756 @default.
• W1969803280 cites W2005704994 @default.
• W1969803280 cites W2008029340 @default.
• W1969803280 cites W2011679013 @default.
• W1969803280 cites W2014643926 @default.
• W1969803280 cites W2024797267 @default.
• W1969803280 cites W2027806294 @default.
• W1969803280 cites W2033395713 @default.
• W1969803280 cites W2035909576 @default.
• W1969803280 cites W2037766564 @default.
• W1969803280 cites W2044189183 @default.
• W1969803280 cites W2046220307 @default.
• W1969803280 cites W2052099337 @default.
• W1969803280 cites W2056468041 @default.
• W1969803280 cites W2069726610 @default.
• W1969803280 cites W2073244152 @default.
• W1969803280 cites W2074726723 @default.
• W1969803280 cites W2077318232 @default.
• W1969803280 cites W2086257736 @default.
• W1969803280 cites W2089187855 @default.
• W1969803280 cites W2094015289 @default.
• W1969803280 cites W2108984473 @default.
• W1969803280 cites W2119017496 @default.
• W1969803280 cites W2119622056 @default.
• W1969803280 cites W2120796546 @default.
• W1969803280 cites W2132157796 @default.
• W1969803280 cites W2139608359 @default.
• W1969803280 cites W2143270595 @default.
• W1969803280 cites W2147924926 @default.
• W1969803280 cites W2503047311 @default.
• W1969803280 cites W2911505078 @default.
• W1969803280 cites W652812635 @default.
• W1969803280 doi "https://doi.org/10.1897/ieam_2007-022.1" @default.
• W1969803280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18260205" @default.
• W1969803280 hasPublicationYear "2008" @default.
• W1969803280 type Work @default.
• W1969803280 sameAs 1969803280 @default.
• W1969803280 citedByCount "102" @default.
• W1969803280 countsByYear W19698032802012 @default.
• W1969803280 countsByYear W19698032802013 @default.
• W1969803280 countsByYear W19698032802014 @default.
• W1969803280 countsByYear W19698032802015 @default.
• W1969803280 countsByYear W19698032802016 @default.
• W1969803280 countsByYear W19698032802017 @default.
• W1969803280 countsByYear W19698032802018 @default.
• W1969803280 countsByYear W19698032802019 @default.
• W1969803280 countsByYear W19698032802020 @default.
• W1969803280 countsByYear W19698032802021 @default.
• W1969803280 countsByYear W19698032802022 @default.
• W1969803280 countsByYear W19698032802023 @default.
• W1969803280 crossrefType "journal-article" @default.
• W1969803280 hasAuthorship W1969803280A5000719992 @default.
• W1969803280 hasAuthorship W1969803280A5025805362 @default.
• W1969803280 hasAuthorship W1969803280A5037316649 @default.
• W1969803280 hasAuthorship W1969803280A5060387940 @default.
• W1969803280 hasAuthorship W1969803280A5080235603 @default.
• W1969803280 hasAuthorship W1969803280A5086719361 @default.
• W1969803280 hasAuthorship W1969803280A5088801421 @default.
• W1969803280 hasAuthorship W1969803280A5091603615 @default.
• W1969803280 hasConcept C107872376 @default.
• W1969803280 hasConcept C127413603 @default.
• W1969803280 hasConcept C142724271 @default.
• W1969803280 hasConcept C147455438 @default.
• W1969803280 hasConcept C175327387 @default.
• W1969803280 hasConcept C185592680 @default.
• W1969803280 hasConcept C187320778 @default.
• W1969803280 hasConcept C18903297 @default.
• W1969803280 hasConcept C2781289450 @default.
• W1969803280 hasConcept C2991714712 @default.
• W1969803280 hasConcept C39432304 @default.
• W1969803280 hasConcept C539469273 @default.
• W1969803280 hasConcept C57442070 @default.
• W1969803280 hasConcept C71924100 @default.
• W1969803280 hasConcept C76886044 @default.
• W1969803280 hasConcept C8625798 @default.
• W1969803280 hasConcept C86803240 @default.
• W1969803280 hasConcept C87717796 @default.

• next