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- W1969804944 abstract "A linear quantitative structure–activity relationship has been developed for a series of para-substituted aromatic sulfonamides by using topological index methodologies. The compounds were studied for their carbonic anhydrase II (CAII) inhibitory activity. A large series of topological indices were calculated and the stepwise regression method was used to derive the most significant model. Very good results were obtained using multi-parametric regressions and showed that the information approach used in the present work is quite useful for modeling carbonic anhydrase inhibition." @default.
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- W1969804944 date "2006-02-01" @default.
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- W1969804944 title "QSAR study on para-substituted aromatic sulfonamides as carbonic anhydrase II inhibitors using topological information indices" @default.
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- W1969804944 doi "https://doi.org/10.1016/j.bmc.2005.09.038" @default.
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