Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969831036> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1969831036 endingPage "181" @default.
- W1969831036 startingPage "177" @default.
- W1969831036 abstract "Microtubules prepared from chick brain homogenates by successive cycles of assembly-disassembly were found to contain two high-molecular-weight proteins, designated microtubule-associated protein1 and microtubule-associated protein2. Microtubule-associated protein2 (apparent molecular weight 300,000 by sodium dodecyl sulfate-polyacrylamide gel electrophoresis) was the preferred substrate for an endogenous cyclic AMP-dependent protein kinase which appeared to be an integral component of the microtubules. The initial rate of phosphorylation of microtubule-associated protein2 was enhanced 4- to 6-fold by cyclic AMP, with half-maximal stimulation occurring at 2 times 10-7 M cyclic AMP. Under optimal conditions, a total of 1.0 and 1.9 mol of phosphate was incorporated per mole of microtubule-associated protein2, in the absence and presence of cyclic AMP, respectively. Cyclic AMP also stimulated the phosphorylation of tubulin, but the rate of phosphate incorporation per mol of tubulin was only 0.15% that of microtubule-associated protein2. The data raise the possibility that the cyclic AMP-dependent phosphorylation of microtubule-associated protein 2 may play a role in microtubule assembly or function." @default.
- W1969831036 created "2016-06-24" @default.
- W1969831036 creator A5032474990 @default.
- W1969831036 creator A5052825834 @default.
- W1969831036 creator A5074245341 @default.
- W1969831036 creator A5083196067 @default.
- W1969831036 date "1975-01-01" @default.
- W1969831036 modified "2023-10-15" @default.
- W1969831036 title "Cyclic AMP-dependent endogenous phosphorylation of a microtubule-associated protein." @default.
- W1969831036 cites W1488233982 @default.
- W1969831036 cites W1538260817 @default.
- W1969831036 cites W1544639113 @default.
- W1969831036 cites W1583635488 @default.
- W1969831036 cites W1775749144 @default.
- W1969831036 cites W1976576149 @default.
- W1969831036 cites W2004617962 @default.
- W1969831036 cites W2005314799 @default.
- W1969831036 cites W2014636427 @default.
- W1969831036 cites W2018289835 @default.
- W1969831036 cites W2026820202 @default.
- W1969831036 cites W2033928631 @default.
- W1969831036 cites W2040047238 @default.
- W1969831036 cites W2044500356 @default.
- W1969831036 cites W2051255332 @default.
- W1969831036 cites W2052352209 @default.
- W1969831036 cites W2067162131 @default.
- W1969831036 cites W2073879684 @default.
- W1969831036 cites W2083328874 @default.
- W1969831036 cites W2100837269 @default.
- W1969831036 cites W2152229168 @default.
- W1969831036 cites W2186044491 @default.
- W1969831036 cites W2274468599 @default.
- W1969831036 cites W2412297940 @default.
- W1969831036 doi "https://doi.org/10.1073/pnas.72.1.177" @default.
- W1969831036 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/432265" @default.
- W1969831036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/164013" @default.
- W1969831036 hasPublicationYear "1975" @default.
- W1969831036 type Work @default.
- W1969831036 sameAs 1969831036 @default.
- W1969831036 citedByCount "487" @default.
- W1969831036 countsByYear W19698310362012 @default.
- W1969831036 countsByYear W19698310362013 @default.
- W1969831036 countsByYear W19698310362014 @default.
- W1969831036 countsByYear W19698310362015 @default.
- W1969831036 countsByYear W19698310362019 @default.
- W1969831036 countsByYear W19698310362023 @default.
- W1969831036 crossrefType "journal-article" @default.
- W1969831036 hasAuthorship W1969831036A5032474990 @default.
- W1969831036 hasAuthorship W1969831036A5052825834 @default.
- W1969831036 hasAuthorship W1969831036A5074245341 @default.
- W1969831036 hasAuthorship W1969831036A5083196067 @default.
- W1969831036 hasBestOaLocation W19698310362 @default.
- W1969831036 hasConcept C116084860 @default.
- W1969831036 hasConcept C11960822 @default.
- W1969831036 hasConcept C12554922 @default.
- W1969831036 hasConcept C16613235 @default.
- W1969831036 hasConcept C185592680 @default.
- W1969831036 hasConcept C20418707 @default.
- W1969831036 hasConcept C2777132085 @default.
- W1969831036 hasConcept C55493867 @default.
- W1969831036 hasConcept C61081601 @default.
- W1969831036 hasConcept C84425145 @default.
- W1969831036 hasConcept C86803240 @default.
- W1969831036 hasConcept C95444343 @default.
- W1969831036 hasConceptScore W1969831036C116084860 @default.
- W1969831036 hasConceptScore W1969831036C11960822 @default.
- W1969831036 hasConceptScore W1969831036C12554922 @default.
- W1969831036 hasConceptScore W1969831036C16613235 @default.
- W1969831036 hasConceptScore W1969831036C185592680 @default.
- W1969831036 hasConceptScore W1969831036C20418707 @default.
- W1969831036 hasConceptScore W1969831036C2777132085 @default.
- W1969831036 hasConceptScore W1969831036C55493867 @default.
- W1969831036 hasConceptScore W1969831036C61081601 @default.
- W1969831036 hasConceptScore W1969831036C84425145 @default.
- W1969831036 hasConceptScore W1969831036C86803240 @default.
- W1969831036 hasConceptScore W1969831036C95444343 @default.
- W1969831036 hasIssue "1" @default.
- W1969831036 hasLocation W19698310361 @default.
- W1969831036 hasLocation W19698310362 @default.
- W1969831036 hasLocation W19698310363 @default.
- W1969831036 hasLocation W19698310364 @default.
- W1969831036 hasOpenAccess W1969831036 @default.
- W1969831036 hasPrimaryLocation W19698310361 @default.
- W1969831036 hasRelatedWork W1901412126 @default.
- W1969831036 hasRelatedWork W1974089612 @default.
- W1969831036 hasRelatedWork W2024145976 @default.
- W1969831036 hasRelatedWork W2031263977 @default.
- W1969831036 hasRelatedWork W2070191397 @default.
- W1969831036 hasRelatedWork W2079016385 @default.
- W1969831036 hasRelatedWork W2107561141 @default.
- W1969831036 hasRelatedWork W2188467511 @default.
- W1969831036 hasRelatedWork W2901583425 @default.
- W1969831036 hasRelatedWork W2528453622 @default.
- W1969831036 hasVolume "72" @default.
- W1969831036 isParatext "false" @default.
- W1969831036 isRetracted "false" @default.
- W1969831036 magId "1969831036" @default.
- W1969831036 workType "article" @default.