FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969858456> ?p ?o ?g. }

• W1969858456 endingPage "5613" @default.
• W1969858456 startingPage "5608" @default.
• W1969858456 abstract "In this work we extended the study of genes controlling the formation of specific differentiation structures called “domes” formed by the rat mammary adenocarcinoma cell line LA7 under the influence of DMSO. We have reported previously that an interferon-inducible gene, rat-8, and the β-subunit of the epithelial sodium channel (ENaC) play a fundamental role in this process. Now, we used a proteomic approach to identify proteins differentially expressed either in DMSO-induced LA7 or in 106A10 cells. Two differentially expressed proteins were investigated. The first, tropomyosin-5b, strongly expressed in DMSO-induced LA7 cells, is needed for dome formation because its synthesis inhibition by the antisense RNA technology abolished domes. The second protein, maspin, strongly expressed in the uninduced 106A10 cell line, inhibits dome formation because 106A10 cells, transfected with rat8 cDNA (the function of which is required for the organization of these structures), acquired the ability to develop domes when cultured in presence of an antimaspin antibody. Dome formation in these cultures are accompanied by ENaC β-subunit expression in the absence of DMSO. Therefore, dome formation requires the expression of tropomyosin-5b, in addition to the ENaC β-subunit and the rat8 proteins, and is under the negative control of maspin." @default.
• W1969858456 created "2016-06-24" @default.
• W1969858456 creator A5001257940 @default.
• W1969858456 creator A5006505062 @default.
• W1969858456 creator A5014662752 @default.
• W1969858456 creator A5020219114 @default.
• W1969858456 creator A5028907602 @default.
• W1969858456 creator A5033940624 @default.
• W1969858456 creator A5036665850 @default.
• W1969858456 creator A5051348948 @default.
• W1969858456 creator A5054191264 @default.
• W1969858456 creator A5059845753 @default.
• W1969858456 creator A5068354706 @default.
• W1969858456 creator A5070777080 @default.
• W1969858456 creator A5077463507 @default.
• W1969858456 creator A5077676515 @default.
• W1969858456 date "2001-05-01" @default.
• W1969858456 modified "2023-09-23" @default.
• W1969858456 title "Proteomic dissection of dome formation in a mammary cell line: Role of tropomyosin-5b and maspin" @default.
• W1969858456 cites W1502713173 @default.
• W1969858456 cites W1505008375 @default.
• W1969858456 cites W1506335912 @default.
• W1969858456 cites W1538390196 @default.
• W1969858456 cites W1547033910 @default.
• W1969858456 cites W176708717 @default.
• W1969858456 cites W1839438061 @default.
• W1969858456 cites W1939368710 @default.
• W1969858456 cites W1967099091 @default.
• W1969858456 cites W1970069848 @default.
• W1969858456 cites W1974872922 @default.
• W1969858456 cites W1981570640 @default.
• W1969858456 cites W1981581392 @default.
• W1969858456 cites W1987955594 @default.
• W1969858456 cites W2001327688 @default.
• W1969858456 cites W2003662074 @default.
• W1969858456 cites W2005673211 @default.
• W1969858456 cites W2006357019 @default.
• W1969858456 cites W2020945775 @default.
• W1969858456 cites W2022961230 @default.
• W1969858456 cites W2030811763 @default.
• W1969858456 cites W2033118701 @default.
• W1969858456 cites W2034687052 @default.
• W1969858456 cites W2046176730 @default.
• W1969858456 cites W2048263097 @default.
• W1969858456 cites W2058128222 @default.
• W1969858456 cites W2058676872 @default.
• W1969858456 cites W2058961362 @default.
• W1969858456 cites W2064878516 @default.
• W1969858456 cites W2067790605 @default.
• W1969858456 cites W2078046706 @default.
• W1969858456 cites W2081013548 @default.
• W1969858456 cites W2087499467 @default.
• W1969858456 cites W2090982434 @default.
• W1969858456 cites W2108963581 @default.
• W1969858456 cites W2110896581 @default.
• W1969858456 cites W2113310577 @default.
• W1969858456 cites W2120035779 @default.
• W1969858456 cites W2123628070 @default.
• W1969858456 cites W2128635872 @default.
• W1969858456 cites W2133813097 @default.
• W1969858456 cites W2134812217 @default.
• W1969858456 cites W2141793288 @default.
• W1969858456 cites W2150566147 @default.
• W1969858456 cites W2159110682 @default.
• W1969858456 cites W2170949754 @default.
• W1969858456 cites W246081158 @default.
• W1969858456 cites W286974496 @default.
• W1969858456 cites W4293247451 @default.
• W1969858456 cites W4294216491 @default.
• W1969858456 doi "https://doi.org/10.1073/pnas.091101898" @default.
• W1969858456 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/33260" @default.
• W1969858456 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11331746" @default.
• W1969858456 hasPublicationYear "2001" @default.
• W1969858456 type Work @default.
• W1969858456 sameAs 1969858456 @default.
• W1969858456 citedByCount "30" @default.
• W1969858456 countsByYear W19698584562012 @default.
• W1969858456 countsByYear W19698584562015 @default.
• W1969858456 countsByYear W19698584562019 @default.
• W1969858456 countsByYear W19698584562020 @default.
• W1969858456 crossrefType "journal-article" @default.
• W1969858456 hasAuthorship W1969858456A5001257940 @default.
• W1969858456 hasAuthorship W1969858456A5006505062 @default.
• W1969858456 hasAuthorship W1969858456A5014662752 @default.
• W1969858456 hasAuthorship W1969858456A5020219114 @default.
• W1969858456 hasAuthorship W1969858456A5028907602 @default.
• W1969858456 hasAuthorship W1969858456A5033940624 @default.
• W1969858456 hasAuthorship W1969858456A5036665850 @default.
• W1969858456 hasAuthorship W1969858456A5051348948 @default.
• W1969858456 hasAuthorship W1969858456A5054191264 @default.
• W1969858456 hasAuthorship W1969858456A5059845753 @default.
• W1969858456 hasAuthorship W1969858456A5068354706 @default.
• W1969858456 hasAuthorship W1969858456A5070777080 @default.
• W1969858456 hasAuthorship W1969858456A5077463507 @default.
• W1969858456 hasAuthorship W1969858456A5077676515 @default.
• W1969858456 hasBestOaLocation W19698584562 @default.
• W1969858456 hasConcept C104292427 @default.
• W1969858456 hasConcept C104317684 @default.

• next