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• W1969900212 abstract "Reconstruction algorithms are presented for a two-step solution of the bioluminescence tomography (BLT) problem. In the first step, a priori anatomical information provided by x-ray computed tomography or by other methods is used to solve the continuous wave (cw) diffuse optical tomography (DOT) problem. A Taylor series expansion approximates the light fluence rate dependence on the optical properties of each region where first and second order direct derivatives of the light fluence rate with respect to scattering and absorption coefficients are obtained and used for the reconstruction. In the second step, the reconstructed optical properties at different wavelengths are used to calculate the Green's function of the system. Then an iterative minimization solution based on the L1 norm shrinks the permissible regions where the sources are allowed by selecting points with higher probability to contribute to the source distribution. This provides an efficient BLT reconstruction algorithm with the ability to determine relative source magnitudes and positions in the presence of noise." @default.
• W1969900212 created "2016-06-24" @default.
• W1969900212 creator A5031021863 @default.
• W1969900212 creator A5050527536 @default.
• W1969900212 date "2010-08-05" @default.
• W1969900212 modified "2023-09-30" @default.
• W1969900212 title "Algorithms for bioluminescence tomography incorporating anatomical information and reconstruction of tissue optical properties" @default.
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• W1969900212 doi "https://doi.org/10.1364/boe.1.000512" @default.
• W1969900212 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3017985" @default.
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