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- W1969903283 abstract "A capillary biosensor is demonstrated which uses the waveguiding properties of the capillary to integrate the signal over an increased surface area without simultaneously increasing the background noise from the detector. This biosensor achieves limits of detection of 30−50 pg/mL in immunoassays using a diode laser for excitation and a PMT for detection. This is ∼2 orders of magnitude greater sensitivity than was achieved using the same immunoassay reagents in a fiber optic biosensor or a planar array biosensor. Two different approaches to using the capillaries as immunosensors are described, either of which could be adapted for multianalyte sensing." @default.
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- W1969903283 date "2001-12-21" @default.
- W1969903283 modified "2023-09-27" @default.
- W1969903283 title "Integrating Waveguide Biosensor" @default.
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- W1969903283 doi "https://doi.org/10.1021/ac015607s" @default.
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