FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969924107> ?p ?o ?g. }

• W1969924107 endingPage "1266" @default.
• W1969924107 startingPage "1259" @default.
• W1969924107 abstract "To determine the effects of continuous low-dose infusion of lipopolysaccharide (LPS) on the expression of E-selectin and intercellular adhesion molecule-1 (ICAM-1) mRNA and neutrophil accumulation in the lungs, liver, spleen, small intestine, and pancreas in dogs.11 healthy adult Beagles.Dogs received a continuous infusion of a low dose (10 microg/kg/h, i.v.) of LPS (Escherichia coli 055:B5) or saline (0.9% NaCI) solution (20 mL/kg/h, i.v.) for 8 hours. Activity levels of tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), and interleukin-6 (1L-6) and the number of WBCs in circulation were examined before and 1, 2, 4, and 8 hours after the onset of LPS infusion. Expression of E-selectin and ICAM-1 mRNA and the number of neutrophils in each tissue were examined.After the onset of LPS infusion, serum TNF-alpha and IL-1beta activities transiently increased. Thereafter, IL-6 activity increased, and high IL-6 activity was maintained throughout the experiment. In dogs in the LPS group, expression of E-selectin mRNA increased only in the lungs, and expression of ICAM-1 mRNA increased in the lungs and liver; the number of neutrophils in the tissue increased in the lungs and liver.Results suggested that expression of E-selectin and ICAM-1 mRNA increased during sepsis, particularly in the lungs and liver, and that this increase was associated with neutrophil accumulation. Hence, inhibiting the activation of endothelial cells in the lung and liver may decrease organ damage caused by accumulated neutrophils and help regulate multiple-organ dysfunction." @default.
• W1969924107 created "2016-06-24" @default.
• W1969924107 creator A5002707883 @default.
• W1969924107 creator A5007429925 @default.
• W1969924107 creator A5024616367 @default.
• W1969924107 creator A5043996165 @default.
• W1969924107 creator A5046263232 @default.
• W1969924107 creator A5075010434 @default.
• W1969924107 creator A5084004470 @default.
• W1969924107 creator A5084399271 @default.
• W1969924107 date "2005-07-01" @default.
• W1969924107 modified "2023-10-06" @default.
• W1969924107 title "Effects of continuous low-dose infusion of lipopolysaccharide on expression of E-selectin and intercellular adhesion molecule-1 messenger RNA and neutrophil accumulation in specific organs in dogs" @default.
• W1969924107 cites W1512082009 @default.
• W1969924107 cites W1945294208 @default.
• W1969924107 cites W1994244260 @default.
• W1969924107 cites W2003399747 @default.
• W1969924107 cites W2011271404 @default.
• W1969924107 cites W2012809855 @default.
• W1969924107 cites W2015531285 @default.
• W1969924107 cites W2018820589 @default.
• W1969924107 cites W2021839146 @default.
• W1969924107 cites W2023105368 @default.
• W1969924107 cites W2024500633 @default.
• W1969924107 cites W2031086429 @default.
• W1969924107 cites W2034930488 @default.
• W1969924107 cites W2044707231 @default.
• W1969924107 cites W2048614712 @default.
• W1969924107 cites W2052303540 @default.
• W1969924107 cites W2052533687 @default.
• W1969924107 cites W2063775889 @default.
• W1969924107 cites W2065506122 @default.
• W1969924107 cites W2067359740 @default.
• W1969924107 cites W2070602276 @default.
• W1969924107 cites W2102862146 @default.
• W1969924107 cites W2102868271 @default.
• W1969924107 cites W2105180121 @default.
• W1969924107 cites W2107801910 @default.
• W1969924107 cites W2126481640 @default.
• W1969924107 cites W2128419820 @default.
• W1969924107 cites W2132237098 @default.
• W1969924107 cites W2136021725 @default.
• W1969924107 cites W2141376163 @default.
• W1969924107 cites W2141868068 @default.
• W1969924107 cites W2143062128 @default.
• W1969924107 cites W2193020186 @default.
• W1969924107 cites W2217215084 @default.
• W1969924107 cites W2334370267 @default.
• W1969924107 cites W2404696820 @default.
• W1969924107 cites W4366064347 @default.
• W1969924107 cites W61048274 @default.
• W1969924107 doi "https://doi.org/10.2460/ajvr.2005.66.1259" @default.
• W1969924107 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16111167" @default.
• W1969924107 hasPublicationYear "2005" @default.
• W1969924107 type Work @default.
• W1969924107 sameAs 1969924107 @default.
• W1969924107 citedByCount "9" @default.
• W1969924107 countsByYear W19699241072012 @default.
• W1969924107 countsByYear W19699241072014 @default.
• W1969924107 countsByYear W19699241072016 @default.
• W1969924107 countsByYear W19699241072021 @default.
• W1969924107 crossrefType "journal-article" @default.
• W1969924107 hasAuthorship W1969924107A5002707883 @default.
• W1969924107 hasAuthorship W1969924107A5007429925 @default.
• W1969924107 hasAuthorship W1969924107A5024616367 @default.
• W1969924107 hasAuthorship W1969924107A5043996165 @default.
• W1969924107 hasAuthorship W1969924107A5046263232 @default.
• W1969924107 hasAuthorship W1969924107A5075010434 @default.
• W1969924107 hasAuthorship W1969924107A5084004470 @default.
• W1969924107 hasAuthorship W1969924107A5084399271 @default.
• W1969924107 hasBestOaLocation W19699241071 @default.
• W1969924107 hasConcept C104317684 @default.
• W1969924107 hasConcept C105580179 @default.
• W1969924107 hasConcept C126322002 @default.
• W1969924107 hasConcept C134018914 @default.
• W1969924107 hasConcept C1491633281 @default.
• W1969924107 hasConcept C16685009 @default.
• W1969924107 hasConcept C17991360 @default.
• W1969924107 hasConcept C185592680 @default.
• W1969924107 hasConcept C199616788 @default.
• W1969924107 hasConcept C203014093 @default.
• W1969924107 hasConcept C2776914184 @default.
• W1969924107 hasConcept C2778384902 @default.
• W1969924107 hasConcept C2778754761 @default.
• W1969924107 hasConcept C2780931953 @default.
• W1969924107 hasConcept C2909375385 @default.
• W1969924107 hasConcept C55493867 @default.
• W1969924107 hasConcept C71924100 @default.
• W1969924107 hasConcept C85789140 @default.
• W1969924107 hasConcept C86803240 @default.
• W1969924107 hasConceptScore W1969924107C104317684 @default.
• W1969924107 hasConceptScore W1969924107C105580179 @default.
• W1969924107 hasConceptScore W1969924107C126322002 @default.
• W1969924107 hasConceptScore W1969924107C134018914 @default.
• W1969924107 hasConceptScore W1969924107C1491633281 @default.
• W1969924107 hasConceptScore W1969924107C16685009 @default.
• W1969924107 hasConceptScore W1969924107C17991360 @default.
• W1969924107 hasConceptScore W1969924107C185592680 @default.

• next