FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969950564> ?p ?o ?g. }

• W1969950564 abstract "Abstract Background To measure the impact of masticatory reduction on learning and memory, previous studies have produced experimental masticatory reduction by modified diet or molar removal. Here we induced spatial learning impairment in mice by reducing masticatory activity and then tested the effect of a combination of environmental enrichment and masticatory rehabilitation in recovering spatial learning at adulthood and in later life. For 6 months (6M) or 18 months (18M), we fed three groups of mice from postnatal day 21 respectively with a hard diet (HD) of pellets; pellets followed by a powdered, soft diet (HD/SD, divided into equal periods); or pellets followed by powder, followed by pellets again (HD/SD/HD, divided into equal periods). To mimic sedentary or active lifestyles, half of the animals from each group were raised from weaning in standard cages (impoverished environment; IE) and the other half in enriched cages (enriched environment; EE). To evaluate spatial learning, we used the Morris water maze. Results IE6M-HD/SD mice showed lower learning rates compared with control (IE6M-HD) or masticatory rehabilitated (IE6MHD/SD/HD) animals. Similarly, EE-HD/SD mice independent of age showed lower performance than controls (EE-HD) or rehabilitated mice (EE-HD/SD/HD). However, combined rehabilitation and EE in aged mice improved learning rate up to control levels. Learning rates did not correlate with swim speed. Conclusions Reduction in masticatory activity imposed on mice previously fed a hard diet (HD/SD) impaired spatial learning in the Morris water maze. In adults, masticatory rehabilitation recovered spatial abilities in both sedentary and active mice, and rehabilitation of masticatory activity combined with EE recovered these losses in aged mice." @default.
• W1969950564 created "2016-06-24" @default.
• W1969950564 creator A5004790511 @default.
• W1969950564 creator A5009042486 @default.
• W1969950564 creator A5009407551 @default.
• W1969950564 creator A5012679115 @default.
• W1969950564 creator A5015808824 @default.
• W1969950564 creator A5020475315 @default.
• W1969950564 creator A5032267155 @default.
• W1969950564 creator A5036388612 @default.
• W1969950564 creator A5044019815 @default.
• W1969950564 creator A5046033634 @default.
• W1969950564 creator A5048717260 @default.
• W1969950564 creator A5059074747 @default.
• W1969950564 creator A5090473903 @default.
• W1969950564 date "2013-06-28" @default.
• W1969950564 modified "2023-09-27" @default.
• W1969950564 title "Enriched environment and masticatory activity rehabilitation recover spatial memory decline in aged mice" @default.
• W1969950564 cites W1788239657 @default.
• W1969950564 cites W1966846364 @default.
• W1969950564 cites W1972702742 @default.
• W1969950564 cites W1982483165 @default.
• W1969950564 cites W1983890419 @default.
• W1969950564 cites W1987163746 @default.
• W1969950564 cites W1991189029 @default.
• W1969950564 cites W1996234041 @default.
• W1969950564 cites W1996299126 @default.
• W1969950564 cites W2000757891 @default.
• W1969950564 cites W2001153527 @default.
• W1969950564 cites W2002072940 @default.
• W1969950564 cites W2006129024 @default.
• W1969950564 cites W2011637750 @default.
• W1969950564 cites W2015661880 @default.
• W1969950564 cites W2017169966 @default.
• W1969950564 cites W2018797541 @default.
• W1969950564 cites W2021292642 @default.
• W1969950564 cites W2026193582 @default.
• W1969950564 cites W2028054867 @default.
• W1969950564 cites W2029497425 @default.
• W1969950564 cites W2031904946 @default.
• W1969950564 cites W2045007926 @default.
• W1969950564 cites W2047930088 @default.
• W1969950564 cites W2052468030 @default.
• W1969950564 cites W2052837971 @default.
• W1969950564 cites W2054944161 @default.
• W1969950564 cites W2056481688 @default.
• W1969950564 cites W2060098116 @default.
• W1969950564 cites W2060849625 @default.
• W1969950564 cites W2062554486 @default.
• W1969950564 cites W2065843454 @default.
• W1969950564 cites W2068911009 @default.
• W1969950564 cites W2070795813 @default.
• W1969950564 cites W2071376829 @default.
• W1969950564 cites W2074748388 @default.
• W1969950564 cites W2091922433 @default.
• W1969950564 cites W2106138734 @default.
• W1969950564 cites W2109557817 @default.
• W1969950564 cites W2110517530 @default.
• W1969950564 cites W2130378710 @default.
• W1969950564 cites W2135014490 @default.
• W1969950564 cites W2136973902 @default.
• W1969950564 cites W2140420845 @default.
• W1969950564 cites W2145458957 @default.
• W1969950564 cites W2154821927 @default.
• W1969950564 cites W2155467021 @default.
• W1969950564 cites W2169473035 @default.
• W1969950564 doi "https://doi.org/10.1186/1471-2202-14-63" @default.
• W1969950564 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3706212" @default.
• W1969950564 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23805920" @default.
• W1969950564 hasPublicationYear "2013" @default.
• W1969950564 type Work @default.
• W1969950564 sameAs 1969950564 @default.
• W1969950564 citedByCount "22" @default.
• W1969950564 countsByYear W19699505642013 @default.
• W1969950564 countsByYear W19699505642015 @default.
• W1969950564 countsByYear W19699505642016 @default.
• W1969950564 countsByYear W19699505642017 @default.
• W1969950564 countsByYear W19699505642018 @default.
• W1969950564 countsByYear W19699505642019 @default.
• W1969950564 countsByYear W19699505642020 @default.
• W1969950564 countsByYear W19699505642021 @default.
• W1969950564 countsByYear W19699505642022 @default.
• W1969950564 countsByYear W19699505642023 @default.
• W1969950564 crossrefType "journal-article" @default.
• W1969950564 hasAuthorship W1969950564A5004790511 @default.
• W1969950564 hasAuthorship W1969950564A5009042486 @default.
• W1969950564 hasAuthorship W1969950564A5009407551 @default.
• W1969950564 hasAuthorship W1969950564A5012679115 @default.
• W1969950564 hasAuthorship W1969950564A5015808824 @default.
• W1969950564 hasAuthorship W1969950564A5020475315 @default.
• W1969950564 hasAuthorship W1969950564A5032267155 @default.
• W1969950564 hasAuthorship W1969950564A5036388612 @default.
• W1969950564 hasAuthorship W1969950564A5044019815 @default.
• W1969950564 hasAuthorship W1969950564A5046033634 @default.
• W1969950564 hasAuthorship W1969950564A5048717260 @default.
• W1969950564 hasAuthorship W1969950564A5059074747 @default.
• W1969950564 hasAuthorship W1969950564A5090473903 @default.
• W1969950564 hasBestOaLocation W19699505641 @default.
• W1969950564 hasConcept C109551439 @default.
• W1969950564 hasConcept C134018914 @default.

• next