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- W1969955955 abstract "Abstract The association of autoimmunity with ataxia telangiectasia and studies linking both immunoglobulin deficiency and thymic deficiencies to autoimmunity prompted our search for anti-thymic antibodies in a patient with ataxia telangiectasia. Immunologic studies revealed both cellular and humoral deficits. An immunoglobulin M complement-dependent antibody which appeared to be specific for T-cells and brain cells was demonstrated by cytotoxicity, immunofluorescence, and absorption studies. A similar antibody was detected in the sera of three patients. We speculate that this is an autoantibody which may be important in the pathogenesis of the disease." @default.
- W1969955955 created "2016-06-24" @default.
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- W1969955955 date "1977-03-01" @default.
- W1969955955 modified "2023-10-16" @default.
- W1969955955 title "Ataxia telangiectasia: An autoimmune disease associated with a cytotoxic antibody to brain and thymus" @default.
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- W1969955955 doi "https://doi.org/10.1016/0090-1229(77)90056-3" @default.
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