Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970007338> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W1970007338 abstract "Introduction Coeliac disease (CD) is a common autoimmune condition affecting 1% of the adult population. However large numbers of patients remain undiagnosed which may have significant health consequences. Guidelines suggest that at least 4 duodenal biopsies should be taken to rule out CD. A previous US study showed that biopsy guidelines were only followed in 35% of cases. The aim of the present study was to see whether guidelines were being followed in the UK and if adherence to the guidelines improved detection of CD. Methods Endoscopy and histology reports were retrospectively reviewed for all patients who had a duodenal biopsy in a 3 month period between November 2012 and January 2013 from 4 UK hospitals. Indications for biopsy, role of the endoscopist, number of duodenal biopsies received by histopathology and the final diagnosis were recorded. The presence of villous atrophy was required for CD diagnosis. Patients were excluded if they had known CD. The difference between a double and single bite biopsy technique was also assessed. Results 1423 patients underwent duodenal biopsy for possible CD across the 4 sites in the study period. 97 (6.8%) of these were diagnosed with CD. Guidelines to take at least 4 biopsies were met in 40% of patients and the median number of duodenal biopsies taken for all patients was 3. CD diagnosis was more likely guidelines were followed (10.1 vs. 4.6% p Conclusion We have shown that 12.4% of patients with CD had a previous gastroscopy 5 years prior to their diagnosis. Taking 4 duodenal biopsies results in increased detection of CD. We are the first investigators to demonstrate variation in biopsy rates based on the speciality of the endoscopist and biopsy technique. Furthermore this variability has a direct relationship with the detection rate of CD. Education of all groups of clinicians in duodenal biopsy techniques may result in more patients receiving a prompt diagnosis of CD. Disclosure of Interest None Declared." @default.
- W1970007338 created "2016-06-24" @default.
- W1970007338 creator A5011373158 @default.
- W1970007338 creator A5019145059 @default.
- W1970007338 creator A5050794885 @default.
- W1970007338 creator A5051743055 @default.
- W1970007338 creator A5068762500 @default.
- W1970007338 creator A5088976611 @default.
- W1970007338 date "2014-05-01" @default.
- W1970007338 modified "2023-09-27" @default.
- W1970007338 title "Su1449 Adherence to Duodenal Biopsy Guidelines Increases the Detection of Coeliac Disease: A Multicentre UK Study" @default.
- W1970007338 doi "https://doi.org/10.1016/s0016-5085(14)61692-9" @default.
- W1970007338 hasPublicationYear "2014" @default.
- W1970007338 type Work @default.
- W1970007338 sameAs 1970007338 @default.
- W1970007338 citedByCount "0" @default.
- W1970007338 crossrefType "journal-article" @default.
- W1970007338 hasAuthorship W1970007338A5011373158 @default.
- W1970007338 hasAuthorship W1970007338A5019145059 @default.
- W1970007338 hasAuthorship W1970007338A5050794885 @default.
- W1970007338 hasAuthorship W1970007338A5051743055 @default.
- W1970007338 hasAuthorship W1970007338A5068762500 @default.
- W1970007338 hasAuthorship W1970007338A5088976611 @default.
- W1970007338 hasConcept C126322002 @default.
- W1970007338 hasConcept C142724271 @default.
- W1970007338 hasConcept C2775934546 @default.
- W1970007338 hasConcept C2778451229 @default.
- W1970007338 hasConcept C2779134260 @default.
- W1970007338 hasConcept C2780349322 @default.
- W1970007338 hasConcept C2908647359 @default.
- W1970007338 hasConcept C2993432164 @default.
- W1970007338 hasConcept C544855455 @default.
- W1970007338 hasConcept C71924100 @default.
- W1970007338 hasConcept C90924648 @default.
- W1970007338 hasConcept C99454951 @default.
- W1970007338 hasConceptScore W1970007338C126322002 @default.
- W1970007338 hasConceptScore W1970007338C142724271 @default.
- W1970007338 hasConceptScore W1970007338C2775934546 @default.
- W1970007338 hasConceptScore W1970007338C2778451229 @default.
- W1970007338 hasConceptScore W1970007338C2779134260 @default.
- W1970007338 hasConceptScore W1970007338C2780349322 @default.
- W1970007338 hasConceptScore W1970007338C2908647359 @default.
- W1970007338 hasConceptScore W1970007338C2993432164 @default.
- W1970007338 hasConceptScore W1970007338C544855455 @default.
- W1970007338 hasConceptScore W1970007338C71924100 @default.
- W1970007338 hasConceptScore W1970007338C90924648 @default.
- W1970007338 hasConceptScore W1970007338C99454951 @default.
- W1970007338 hasLocation W19700073381 @default.
- W1970007338 hasOpenAccess W1970007338 @default.
- W1970007338 hasPrimaryLocation W19700073381 @default.
- W1970007338 hasRelatedWork W2023083046 @default.
- W1970007338 hasRelatedWork W2045850612 @default.
- W1970007338 hasRelatedWork W2105878669 @default.
- W1970007338 hasRelatedWork W2105929939 @default.
- W1970007338 hasRelatedWork W2118518163 @default.
- W1970007338 hasRelatedWork W2135773513 @default.
- W1970007338 hasRelatedWork W2137975849 @default.
- W1970007338 hasRelatedWork W2152473522 @default.
- W1970007338 hasRelatedWork W2202890909 @default.
- W1970007338 hasRelatedWork W2317493710 @default.
- W1970007338 hasRelatedWork W2318517161 @default.
- W1970007338 hasRelatedWork W2330754146 @default.
- W1970007338 hasRelatedWork W2344326628 @default.
- W1970007338 hasRelatedWork W2387717773 @default.
- W1970007338 hasRelatedWork W2414122514 @default.
- W1970007338 hasRelatedWork W2417614954 @default.
- W1970007338 hasRelatedWork W2552979554 @default.
- W1970007338 hasRelatedWork W2554793724 @default.
- W1970007338 hasRelatedWork W2566463697 @default.
- W1970007338 hasRelatedWork W2744470142 @default.
- W1970007338 isParatext "false" @default.
- W1970007338 isRetracted "false" @default.
- W1970007338 magId "1970007338" @default.
- W1970007338 workType "article" @default.