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- W1970011211 abstract "Quinine increases the conductance of hemi-gap junctions in horizontal cells. We investigated the mechanisms of alkalinization and the hypothesis that quinine-induced alkalinization produced these conductance increases. We found that quinine-induced alkalinizations were not blocked by cobalt, amiloridie, or DIDS. Therefore, this suggests that the alkalinization is not likely due to net proton flux through opened hemi-gap channels nor is it likely due to an action on Cl−/HC03− exchanger or Na+/H+ exchanger, both of which are known to regulate pHi in the horizontal cells. Quinine increased hemi-gap conductance even when cells were recorded with patch pipets containing up to 80 mM HEPES. We conclude that quinine-induced alkalinization cannot account solely for the hemi-gap junctional conductance increases." @default.
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- W1970011211 date "1996-12-01" @default.
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- W1970011211 title "Quinine, intracellular pH and modulation of hemi-gap junctions in catfish horizontal cells" @default.
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- W1970011211 doi "https://doi.org/10.1016/s0042-6989(96)00129-0" @default.
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