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• W1970013273 endingPage "9860" @default.
• W1970013273 startingPage "9843" @default.
• W1970013273 abstract "To determine the genetic elements required for modulation of ornithine decarboxylase (ODC) activity in response to cell growth or treatment with serum or with tetradecanoyl phorbol acetate, ODC deficient cells were transfected with a series of recombinant DNAs encoding mouse ODC. All of the transfected cells expressing an intact mouse ODC protein displayed regulation of ODC activity, including those expressing a construct deprived of all ODC-specific sequence information except the protein-coding region. ODC mRNA changed much less than enzymatic activity. A mutation of the protein-coding region that converted ODC from an unstable to a stable intracellular protein attenuated the regulatory response. We conclude that post-transcriptional events associated with ODC degradation dominate the response to these stimuli." @default.
• W1970013273 created "2016-06-24" @default.
• W1970013273 creator A5015312742 @default.
• W1970013273 creator A5052009722 @default.
• W1970013273 creator A5056968806 @default.
• W1970013273 date "1989-01-01" @default.
• W1970013273 modified "2023-09-25" @default.
• W1970013273 title "Regulation of mouse ornithine decarboxylase activity by cell growth, serum and tetradecanoyl phorbol acetate is governed primarily by sequences within the coding region of the gene" @default.
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• W1970013273 doi "https://doi.org/10.1093/nar/17.23.9843" @default.
• W1970013273 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/335218" @default.
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• W1970013273 hasPublicationYear "1989" @default.
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