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- W1970028166 abstract "Gap junctions containing extensive, highly ordered crystalline arrays of hexagonally packed connexons have been isolated from the hepatopancreas of the arthropod, Homarus americanus (American lobster). The structure of such junctions has been studied to a resolution of ∼ 25 Å in three dimensions by electron microscopy of negatively stained specimens. The structure, which has the crystallographic symmetry of the two-sided plane group p6, reveals the connexon as an annular oligomer which projects ∼30–45 Å from the cytoplasmic surface. The stain-filled channel structure appears to be ∼40–45 Å wide in the extracellular region. Projection images of glucose-embedded specimens extend to a resolution of 10 Å, and show a strong contrast from the connexon subunits. Overall the structure is quite similar to that of rat liver junctions, except that less stain is seen in the aqueous region of the gap and more surrounding the protrusions of the protein into the cytoplasm." @default.
- W1970028166 created "2016-06-24" @default.
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- W1970028166 date "1991-06-01" @default.
- W1970028166 modified "2023-09-26" @default.
- W1970028166 title "Three-dimensional structure of an invertebrate intercellular communicating junction" @default.
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- W1970028166 doi "https://doi.org/10.1016/1047-8477(91)90075-8" @default.
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