FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970031270> ?p ?o ?g. }

• W1970031270 endingPage "2218" @default.
• W1970031270 startingPage "2207" @default.
• W1970031270 abstract "Chordomas are locally destructive tumors with high rates of recurrence and a poor prognosis. The mechanisms involved in chordoma recurrence remain largely unknown. In the present study, we examined the proteomic profile of a chordoma primary tumor (CSO) and a recurrent tumor (CSR) through mass spectrum in a chordoma patient who underwent surgery. Bioinformatic analysis of the profile showed that 359 proteins had a significant expression difference and 21 pathways had a striking alteration between the CSO and the CSR. The CSR showed a significant increase in carbohydrate metabolism. Immunohistochemistry (IHC) confirmed that the cancer stem cell marker activated leukocyte cell adhesion molecule (ALCAM or CD166) expression level was higher in the recurrent than that in the primary tumor. The present study analyzed the proteomic profile change between CSO and CSR and identified a new biomarker ALCAM in recurrent chordomas. This finding sheds light on unraveling the pathophysiology of chordoma recurrence and on exploring more effective prognostic biomarkers and targeted therapies against this devastating disease." @default.
• W1970031270 created "2016-06-24" @default.
• W1970031270 creator A5001827004 @default.
• W1970031270 creator A5010293813 @default.
• W1970031270 creator A5010335845 @default.
• W1970031270 creator A5011872217 @default.
• W1970031270 creator A5030942972 @default.
• W1970031270 creator A5044069774 @default.
• W1970031270 creator A5067212579 @default.
• W1970031270 creator A5067874901 @default.
• W1970031270 creator A5086896399 @default.
• W1970031270 creator A5090284969 @default.
• W1970031270 date "2015-02-26" @default.
• W1970031270 modified "2023-10-12" @default.
• W1970031270 title "Differential proteomic profiling of primary and recurrent chordomas" @default.
• W1970031270 cites W146375978 @default.
• W1970031270 cites W1876073362 @default.
• W1970031270 cites W1948398064 @default.
• W1970031270 cites W1964545873 @default.
• W1970031270 cites W1971742491 @default.
• W1970031270 cites W1973372083 @default.
• W1970031270 cites W1987090313 @default.
• W1970031270 cites W2006798082 @default.
• W1970031270 cites W2009226890 @default.
• W1970031270 cites W2021371565 @default.
• W1970031270 cites W2021657948 @default.
• W1970031270 cites W2037199116 @default.
• W1970031270 cites W2068196799 @default.
• W1970031270 cites W2075824380 @default.
• W1970031270 cites W2082085770 @default.
• W1970031270 cites W2089960919 @default.
• W1970031270 cites W2094378306 @default.
• W1970031270 cites W2103953491 @default.
• W1970031270 cites W2112253005 @default.
• W1970031270 cites W2121411279 @default.
• W1970031270 cites W2125315196 @default.
• W1970031270 cites W2125608517 @default.
• W1970031270 cites W2148342439 @default.
• W1970031270 cites W2151411303 @default.
• W1970031270 cites W2163410951 @default.
• W1970031270 cites W2164154943 @default.
• W1970031270 cites W2168331112 @default.
• W1970031270 cites W2256368028 @default.
• W1970031270 doi "https://doi.org/10.3892/or.2015.3818" @default.
• W1970031270 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25738923" @default.
• W1970031270 hasPublicationYear "2015" @default.
• W1970031270 type Work @default.
• W1970031270 sameAs 1970031270 @default.
• W1970031270 citedByCount "7" @default.
• W1970031270 countsByYear W19700312702019 @default.
• W1970031270 countsByYear W19700312702020 @default.
• W1970031270 countsByYear W19700312702021 @default.
• W1970031270 countsByYear W19700312702022 @default.
• W1970031270 crossrefType "journal-article" @default.
• W1970031270 hasAuthorship W1970031270A5001827004 @default.
• W1970031270 hasAuthorship W1970031270A5010293813 @default.
• W1970031270 hasAuthorship W1970031270A5010335845 @default.
• W1970031270 hasAuthorship W1970031270A5011872217 @default.
• W1970031270 hasAuthorship W1970031270A5030942972 @default.
• W1970031270 hasAuthorship W1970031270A5044069774 @default.
• W1970031270 hasAuthorship W1970031270A5067212579 @default.
• W1970031270 hasAuthorship W1970031270A5067874901 @default.
• W1970031270 hasAuthorship W1970031270A5086896399 @default.
• W1970031270 hasAuthorship W1970031270A5090284969 @default.
• W1970031270 hasBestOaLocation W19700312701 @default.
• W1970031270 hasConcept C121608353 @default.
• W1970031270 hasConcept C126322002 @default.
• W1970031270 hasConcept C142724271 @default.
• W1970031270 hasConcept C143998085 @default.
• W1970031270 hasConcept C16224149 @default.
• W1970031270 hasConcept C203014093 @default.
• W1970031270 hasConcept C204232928 @default.
• W1970031270 hasConcept C2780456743 @default.
• W1970031270 hasConcept C2781018059 @default.
• W1970031270 hasConcept C2781190729 @default.
• W1970031270 hasConcept C2781197716 @default.
• W1970031270 hasConcept C29537977 @default.
• W1970031270 hasConcept C502942594 @default.
• W1970031270 hasConcept C54355233 @default.
• W1970031270 hasConcept C67082663 @default.
• W1970031270 hasConcept C71924100 @default.
• W1970031270 hasConcept C86803240 @default.
• W1970031270 hasConceptScore W1970031270C121608353 @default.
• W1970031270 hasConceptScore W1970031270C126322002 @default.
• W1970031270 hasConceptScore W1970031270C142724271 @default.
• W1970031270 hasConceptScore W1970031270C143998085 @default.
• W1970031270 hasConceptScore W1970031270C16224149 @default.
• W1970031270 hasConceptScore W1970031270C203014093 @default.
• W1970031270 hasConceptScore W1970031270C204232928 @default.
• W1970031270 hasConceptScore W1970031270C2780456743 @default.
• W1970031270 hasConceptScore W1970031270C2781018059 @default.
• W1970031270 hasConceptScore W1970031270C2781190729 @default.
• W1970031270 hasConceptScore W1970031270C2781197716 @default.
• W1970031270 hasConceptScore W1970031270C29537977 @default.
• W1970031270 hasConceptScore W1970031270C502942594 @default.
• W1970031270 hasConceptScore W1970031270C54355233 @default.
• W1970031270 hasConceptScore W1970031270C67082663 @default.
• W1970031270 hasConceptScore W1970031270C71924100 @default.

• next