Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970034054> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1970034054 endingPage "319" @default.
- W1970034054 startingPage "314" @default.
- W1970034054 abstract "Procedures for peptide bond formation using esters of l ‐amino acids as the acyl donor and secondary amines such as derivatives of d ‐ or l ‐proline, or pyroglutamic acid as the nucleophile in anhydrous 2‐methyl‐2‐propanol catalyzed by alcalase or subtilisin Carlsberg have been developed. Kinetic studies have shown that all secondary amines tested had catalytic efficiencies (κ cat /κ m ) in the range 84–423 min −1 M −1 . Both enzymes have identical catalytic properties. The selectivity of the enzyme‐catalyzed reaction in 2‐methyl‐2‐propanol shows that at the s ‐1 subsite of the enzyme only l ‐amino acids are substrates as acyl donors, and at the s ‐1′ subsite both d ‐ and l ‐amino acids are substrates. Optimal conditions for preparing precursors of the renin inhibitors Z‐Ala‐Pro‐OBzl, Z‐Lys(Z)‐Pro‐OBzl and Z‐Lys(TFA)‐Pro‐OBzl were studied." @default.
- W1970034054 created "2016-06-24" @default.
- W1970034054 creator A5064314691 @default.
- W1970034054 creator A5068377012 @default.
- W1970034054 creator A5076382534 @default.
- W1970034054 date "1995-09-01" @default.
- W1970034054 modified "2023-10-03" @default.
- W1970034054 title "Alkaline protease catalysis of a secondary amine to form a peptide bond" @default.
- W1970034054 cites W1499739398 @default.
- W1970034054 cites W1963559630 @default.
- W1970034054 cites W1971022925 @default.
- W1970034054 cites W1977575458 @default.
- W1970034054 cites W1984978155 @default.
- W1970034054 cites W1992987020 @default.
- W1970034054 cites W1994814731 @default.
- W1970034054 cites W1995032211 @default.
- W1970034054 cites W1997481137 @default.
- W1970034054 cites W1999563041 @default.
- W1970034054 cites W2008869811 @default.
- W1970034054 cites W2024129937 @default.
- W1970034054 cites W2030082109 @default.
- W1970034054 cites W2053052767 @default.
- W1970034054 cites W2061268022 @default.
- W1970034054 cites W2073434308 @default.
- W1970034054 cites W2073723813 @default.
- W1970034054 cites W2084641591 @default.
- W1970034054 cites W2105800282 @default.
- W1970034054 cites W2021944485 @default.
- W1970034054 doi "https://doi.org/10.1111/j.1399-3011.1995.tb00603.x" @default.
- W1970034054 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8537185" @default.
- W1970034054 hasPublicationYear "1995" @default.
- W1970034054 type Work @default.
- W1970034054 sameAs 1970034054 @default.
- W1970034054 citedByCount "12" @default.
- W1970034054 countsByYear W19700340542012 @default.
- W1970034054 countsByYear W19700340542018 @default.
- W1970034054 crossrefType "journal-article" @default.
- W1970034054 hasAuthorship W1970034054A5064314691 @default.
- W1970034054 hasAuthorship W1970034054A5068377012 @default.
- W1970034054 hasAuthorship W1970034054A5076382534 @default.
- W1970034054 hasConcept C118792377 @default.
- W1970034054 hasConcept C131779359 @default.
- W1970034054 hasConcept C161790260 @default.
- W1970034054 hasConcept C178790620 @default.
- W1970034054 hasConcept C178907741 @default.
- W1970034054 hasConcept C181199279 @default.
- W1970034054 hasConcept C185592680 @default.
- W1970034054 hasConcept C187714232 @default.
- W1970034054 hasConcept C2776714187 @default.
- W1970034054 hasConcept C2779281246 @default.
- W1970034054 hasConcept C2779811187 @default.
- W1970034054 hasConcept C31684184 @default.
- W1970034054 hasConcept C41183919 @default.
- W1970034054 hasConcept C515207424 @default.
- W1970034054 hasConcept C55493867 @default.
- W1970034054 hasConcept C71240020 @default.
- W1970034054 hasConcept C87282627 @default.
- W1970034054 hasConceptScore W1970034054C118792377 @default.
- W1970034054 hasConceptScore W1970034054C131779359 @default.
- W1970034054 hasConceptScore W1970034054C161790260 @default.
- W1970034054 hasConceptScore W1970034054C178790620 @default.
- W1970034054 hasConceptScore W1970034054C178907741 @default.
- W1970034054 hasConceptScore W1970034054C181199279 @default.
- W1970034054 hasConceptScore W1970034054C185592680 @default.
- W1970034054 hasConceptScore W1970034054C187714232 @default.
- W1970034054 hasConceptScore W1970034054C2776714187 @default.
- W1970034054 hasConceptScore W1970034054C2779281246 @default.
- W1970034054 hasConceptScore W1970034054C2779811187 @default.
- W1970034054 hasConceptScore W1970034054C31684184 @default.
- W1970034054 hasConceptScore W1970034054C41183919 @default.
- W1970034054 hasConceptScore W1970034054C515207424 @default.
- W1970034054 hasConceptScore W1970034054C55493867 @default.
- W1970034054 hasConceptScore W1970034054C71240020 @default.
- W1970034054 hasConceptScore W1970034054C87282627 @default.
- W1970034054 hasIssue "3-4" @default.
- W1970034054 hasLocation W19700340541 @default.
- W1970034054 hasLocation W19700340542 @default.
- W1970034054 hasOpenAccess W1970034054 @default.
- W1970034054 hasPrimaryLocation W19700340541 @default.
- W1970034054 hasRelatedWork W1987375010 @default.
- W1970034054 hasRelatedWork W1994651367 @default.
- W1970034054 hasRelatedWork W2021939235 @default.
- W1970034054 hasRelatedWork W2027569059 @default.
- W1970034054 hasRelatedWork W2029275114 @default.
- W1970034054 hasRelatedWork W2050670747 @default.
- W1970034054 hasRelatedWork W2403947567 @default.
- W1970034054 hasRelatedWork W2952071652 @default.
- W1970034054 hasRelatedWork W3012348287 @default.
- W1970034054 hasRelatedWork W4309258849 @default.
- W1970034054 hasVolume "46" @default.
- W1970034054 isParatext "false" @default.
- W1970034054 isRetracted "false" @default.
- W1970034054 magId "1970034054" @default.
- W1970034054 workType "article" @default.