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- W1970042118 abstract "SUMMARY The effects of oestradiol, diethylstilboestrol, α,α′-dimethylstilbene-4,4′-diol (DMS), α-ethyl-α′-methylstilbene-4,4′-diol (MES), meso -hexoestrol, dl -hexoestrol, meso -butoestrol, dl -butoestroland erythro -α-ethyl-α′-methyl-4,4′-dihydroxybibenzyl ( erythro -MEA) on the incorporation of tritiated uridine into uterine RNA were investigated. At 2 hr., valid relative potency estimates with oestradiol were obtained with all substances, and MES, erythro -MEA and meso -butoestrol were almost as potent as diethylstilboestrol and meso -hexoestrol. The time-course of the uridine response to the different substances varied markedly. Injections every 16 hr. of DMS, MES, dl -hexoestrol, meso -butoestrol and erythro -MEA elicited little uterine or vaginal growth, but small doses of these substances given every 4 hr. elicited considerable growth in both organs. It was concluded that the compounds tested were oestrogens and not pro-oestrogens." @default.
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- W1970042118 date "1969-09-01" @default.
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- W1970042118 title "THE OESTROGENIC POTENCY IN THE MOUSE OF SEVERAL SUBSTANCES CLOSELY RELATED TO DIETHYLSTILBOESTROL AND MESO-HEXOESTROL" @default.
- W1970042118 doi "https://doi.org/10.1677/joe.0.0450009" @default.
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