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- W1970061164 abstract "An attempt was made to correlate the known antimotion sickness properties of six drugs in man with their ability to protect against drug-induced emesis in the pigeon. Digitoxin and alkavervir were used as the challenging emetics. Three of the six antiemetics were found to produce an emetic response in the pigeon (cyclizine HCl, dimenhydrinate, and diphenhydramine HCl). The remaining three (chlorcyclizine HCl, chlorpromazine HCl, and meclizine HCl) gave no protection against digi-toxin-induced emesis. Chlorcyclizine HCl and meclizine HCl protected the animal against alkavervir-induced emesis. Correlation between man and the pigeon for emetic/antiemetic responses was found to be poor." @default.
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- W1970061164 date "1957-02-01" @default.
- W1970061164 modified "2023-09-26" @default.
- W1970061164 title "Antiemetics in the Pigeon**College of Pharmacy, Ohio State University, Columbus 10" @default.
- W1970061164 doi "https://doi.org/10.1002/jps.3030460217" @default.
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