FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970081070> ?p ?o ?g. }

• W1970081070 endingPage "154" @default.
• W1970081070 startingPage "150" @default.
• W1970081070 abstract "To assess the effect of ethnicity, the association of WC, WHR and hypertension along with PGC-1α (Gly482Ser), UCP2 -866 G/A and SIRT1 -1400 T/C polymorphisms in seven endogamous caste groups and pooled population of Punjab.Study was conducted on 1813 individuals (859 T2D patients and 954 healthy controls) belonging to seven endogamous groups. Waist and hip circumference, height, weight and blood pressure were recorded following standard protocol using designed performa. PGC-1α (Gly482Ser) and UCP2 -866 G/A polymorphisms were genotyped using PCR RFLP and SIRT1 -1400 T/C was genotyped by direct DNA sequencing.WHR conferred risk in Brahmins (p=0.00003), Khtaris (p=0.001) and SCs (p=0.02). Similarly, we detected that WC conferred risk in BCs (p=0.012), Brahmins (p=0.016), Jat Sikhs (0.00025), Khatris (0.005) and SCs (p=0.015). In pooled population, all three factors imparted risk (WHR (p=0.00001), hypertension (p=0.003) and WC (p=0.0000016)). With respect to gene polymorphism, PGC-1α (Gly482Ser) was associated in Banias (p=0.0003), Jat Sikhs (p=0.003) and Khatris (p=0.03). Similarly, UCP2 -866 G>A showed risk in Banias (p=0.000004), BCs (p=0.01) and SCs (p=0.01). However, SIRT1 -1400 T>C showed risk only in Khatris (p=0.004). In the pooled population of Punjab, both PGC-1α (Gly482Ser) [p=0.001] and UCP2 -866 G>A (p=0.0001) polymorphisms provided risk. Interaction analysis showed 72% of the patients had risk combination of PGC-1α XA and UCP2-866 XA genotypes.Based on the data, Khatris were found to be showing the highest susceptibility to T2D followed by SCs. Different combinations of factors provided risk in each caste group and in pooled population. Therefore, to curve the menace of T2D, detailed information about the ethnic background of the individual will be very useful for proper medical intervention." @default.
• W1970081070 created "2016-06-24" @default.
• W1970081070 creator A5003822825 @default.
• W1970081070 creator A5037765992 @default.
• W1970081070 creator A5044408150 @default.
• W1970081070 date "2015-06-01" @default.
• W1970081070 modified "2023-10-18" @default.
• W1970081070 title "The influence of ethnicity in the association of WC, WHR, hypertension and PGC-1α (Gly482Ser), UCP2 − 866 G/A and SIRT1 − 1400 T/C polymorphisms with T2D in the population of Punjab" @default.
• W1970081070 cites W1522893416 @default.
• W1970081070 cites W1569424076 @default.
• W1970081070 cites W1964037904 @default.
• W1970081070 cites W1964203123 @default.
• W1970081070 cites W1969445144 @default.
• W1970081070 cites W1978215768 @default.
• W1970081070 cites W1984668213 @default.
• W1970081070 cites W1984703824 @default.
• W1970081070 cites W2000786855 @default.
• W1970081070 cites W2021241462 @default.
• W1970081070 cites W2022521362 @default.
• W1970081070 cites W2022889587 @default.
• W1970081070 cites W2028980494 @default.
• W1970081070 cites W2037976825 @default.
• W1970081070 cites W2038718616 @default.
• W1970081070 cites W2050464698 @default.
• W1970081070 cites W2058481760 @default.
• W1970081070 cites W2059267070 @default.
• W1970081070 cites W2059691964 @default.
• W1970081070 cites W2066503141 @default.
• W1970081070 cites W2067561975 @default.
• W1970081070 cites W2068934587 @default.
• W1970081070 cites W2071348149 @default.
• W1970081070 cites W2071817929 @default.
• W1970081070 cites W2078839691 @default.
• W1970081070 cites W2079209341 @default.
• W1970081070 cites W2079323899 @default.
• W1970081070 cites W2079458541 @default.
• W1970081070 cites W2089347873 @default.
• W1970081070 cites W2097918979 @default.
• W1970081070 cites W2100445405 @default.
• W1970081070 cites W2101508556 @default.
• W1970081070 cites W2101953986 @default.
• W1970081070 cites W2106650290 @default.
• W1970081070 cites W2107416606 @default.
• W1970081070 cites W2138037300 @default.
• W1970081070 cites W2140421073 @default.
• W1970081070 cites W2143954917 @default.
• W1970081070 cites W2145279264 @default.
• W1970081070 cites W2153684035 @default.
• W1970081070 cites W2156574254 @default.
• W1970081070 cites W2159204230 @default.
• W1970081070 cites W2160176350 @default.
• W1970081070 cites W2334899541 @default.
• W1970081070 cites W4232138652 @default.
• W1970081070 cites W4244084604 @default.
• W1970081070 cites W4297904989 @default.
• W1970081070 doi "https://doi.org/10.1016/j.gene.2015.03.019" @default.
• W1970081070 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25773007" @default.
• W1970081070 hasPublicationYear "2015" @default.
• W1970081070 type Work @default.
• W1970081070 sameAs 1970081070 @default.
• W1970081070 citedByCount "10" @default.
• W1970081070 countsByYear W19700810702015 @default.
• W1970081070 countsByYear W19700810702016 @default.
• W1970081070 countsByYear W19700810702017 @default.
• W1970081070 countsByYear W19700810702018 @default.
• W1970081070 countsByYear W19700810702019 @default.
• W1970081070 countsByYear W19700810702020 @default.
• W1970081070 countsByYear W19700810702022 @default.
• W1970081070 crossrefType "journal-article" @default.
• W1970081070 hasAuthorship W1970081070A5003822825 @default.
• W1970081070 hasAuthorship W1970081070A5037765992 @default.
• W1970081070 hasAuthorship W1970081070A5044408150 @default.
• W1970081070 hasConcept C126322002 @default.
• W1970081070 hasConcept C134018914 @default.
• W1970081070 hasConcept C144024400 @default.
• W1970081070 hasConcept C149923435 @default.
• W1970081070 hasConcept C165087160 @default.
• W1970081070 hasConcept C2776193436 @default.
• W1970081070 hasConcept C2908647359 @default.
• W1970081070 hasConcept C511355011 @default.
• W1970081070 hasConcept C54355233 @default.
• W1970081070 hasConcept C71924100 @default.
• W1970081070 hasConcept C86803240 @default.
• W1970081070 hasConceptScore W1970081070C126322002 @default.
• W1970081070 hasConceptScore W1970081070C134018914 @default.
• W1970081070 hasConceptScore W1970081070C144024400 @default.
• W1970081070 hasConceptScore W1970081070C149923435 @default.
• W1970081070 hasConceptScore W1970081070C165087160 @default.
• W1970081070 hasConceptScore W1970081070C2776193436 @default.
• W1970081070 hasConceptScore W1970081070C2908647359 @default.
• W1970081070 hasConceptScore W1970081070C511355011 @default.
• W1970081070 hasConceptScore W1970081070C54355233 @default.
• W1970081070 hasConceptScore W1970081070C71924100 @default.
• W1970081070 hasConceptScore W1970081070C86803240 @default.
• W1970081070 hasFunder F4320320717 @default.
• W1970081070 hasIssue "2" @default.
• W1970081070 hasLocation W19700810701 @default.
• W1970081070 hasLocation W19700810702 @default.

• next