Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970124511> ?p ?o ?g. }
- W1970124511 abstract "The vitamin D receptor (VDR) is a nuclear, ligand-dependent transcription factor that in complex with hormonally active vitamin D, 1,25(OH)2D3, regulates the expression of more than 900 genes involved in a wide array of physiological functions. The impact of 1,25(OH)2D3-VDR signaling on immune function has been the focus of many recent studies as a link between 1,25(OH)2D3 and susceptibility to various infections and to development of a variety of inflammatory diseases has been suggested. It is also becoming increasingly clear that microbes slow down immune reactivity by dysregulating the VDR ultimately to increase their chance of survival. Immune modulatory therapies that enhance VDR expression and activity are therefore considered in the clinic today to a greater extent. As T cells are of great importance for both protective immunity and development of inflammatory diseases a variety of studies have been engaged investigating the impact of VDR expression in T cells and found that VDR expression and activity plays an important role in both T cell development, differentiation and effector function. In this review we will analyze current knowledge of VDR regulation and function in T cells and discuss its importance for immune activity." @default.
- W1970124511 created "2016-06-24" @default.
- W1970124511 creator A5028179390 @default.
- W1970124511 creator A5028590821 @default.
- W1970124511 creator A5061619582 @default.
- W1970124511 creator A5070281131 @default.
- W1970124511 date "2013-01-01" @default.
- W1970124511 modified "2023-09-30" @default.
- W1970124511 title "The Vitamin D Receptor and T Cell Function" @default.
- W1970124511 cites W1521828067 @default.
- W1970124511 cites W1547710551 @default.
- W1970124511 cites W1562107474 @default.
- W1970124511 cites W1579725476 @default.
- W1970124511 cites W1613446635 @default.
- W1970124511 cites W1656450967 @default.
- W1970124511 cites W1657528050 @default.
- W1970124511 cites W1663317712 @default.
- W1970124511 cites W1858750897 @default.
- W1970124511 cites W1927684145 @default.
- W1970124511 cites W1968457230 @default.
- W1970124511 cites W1970548110 @default.
- W1970124511 cites W1972300087 @default.
- W1970124511 cites W1977290996 @default.
- W1970124511 cites W1977628938 @default.
- W1970124511 cites W1981022538 @default.
- W1970124511 cites W1983435743 @default.
- W1970124511 cites W1983885843 @default.
- W1970124511 cites W1984593949 @default.
- W1970124511 cites W1984820389 @default.
- W1970124511 cites W1985073208 @default.
- W1970124511 cites W1986463324 @default.
- W1970124511 cites W1987040411 @default.
- W1970124511 cites W1988506918 @default.
- W1970124511 cites W1988738875 @default.
- W1970124511 cites W1988897354 @default.
- W1970124511 cites W1990777169 @default.
- W1970124511 cites W1992204488 @default.
- W1970124511 cites W1993051112 @default.
- W1970124511 cites W1996785396 @default.
- W1970124511 cites W1997349093 @default.
- W1970124511 cites W1998169884 @default.
- W1970124511 cites W2001478757 @default.
- W1970124511 cites W2002857704 @default.
- W1970124511 cites W2003322712 @default.
- W1970124511 cites W2003928686 @default.
- W1970124511 cites W2007223760 @default.
- W1970124511 cites W2007331929 @default.
- W1970124511 cites W2007751085 @default.
- W1970124511 cites W2008374372 @default.
- W1970124511 cites W2011382235 @default.
- W1970124511 cites W2017851530 @default.
- W1970124511 cites W2029081372 @default.
- W1970124511 cites W2031554681 @default.
- W1970124511 cites W2032042758 @default.
- W1970124511 cites W2033561829 @default.
- W1970124511 cites W2033809293 @default.
- W1970124511 cites W2034742236 @default.
- W1970124511 cites W2037287388 @default.
- W1970124511 cites W2038177382 @default.
- W1970124511 cites W2040112038 @default.
- W1970124511 cites W2044310665 @default.
- W1970124511 cites W2047229085 @default.
- W1970124511 cites W2048662055 @default.
- W1970124511 cites W2049020751 @default.
- W1970124511 cites W2050712584 @default.
- W1970124511 cites W2052097669 @default.
- W1970124511 cites W2052505493 @default.
- W1970124511 cites W2056027443 @default.
- W1970124511 cites W2056962768 @default.
- W1970124511 cites W2057921492 @default.
- W1970124511 cites W2058684713 @default.
- W1970124511 cites W2058750989 @default.
- W1970124511 cites W2058838706 @default.
- W1970124511 cites W2064257381 @default.
- W1970124511 cites W2064935896 @default.
- W1970124511 cites W2065321690 @default.
- W1970124511 cites W2066668961 @default.
- W1970124511 cites W2072108911 @default.
- W1970124511 cites W2072268467 @default.
- W1970124511 cites W2074559070 @default.
- W1970124511 cites W2076889101 @default.
- W1970124511 cites W2078958508 @default.
- W1970124511 cites W2081559552 @default.
- W1970124511 cites W2086086320 @default.
- W1970124511 cites W2088412514 @default.
- W1970124511 cites W2088705717 @default.
- W1970124511 cites W2091987454 @default.
- W1970124511 cites W2092406421 @default.
- W1970124511 cites W2094375093 @default.
- W1970124511 cites W2097302700 @default.
- W1970124511 cites W2102405170 @default.
- W1970124511 cites W2103024679 @default.
- W1970124511 cites W2104457498 @default.
- W1970124511 cites W2108279958 @default.
- W1970124511 cites W2113537333 @default.
- W1970124511 cites W2116296059 @default.
- W1970124511 cites W2118149184 @default.
- W1970124511 cites W2118307385 @default.
- W1970124511 cites W2119745788 @default.
- W1970124511 cites W2121096379 @default.