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- W1970168579 abstract "The paper discusses the properties of models used to estimate the deposition of aerosols in the human respiratory tract. The deposition equations used in these models differ from each other as well as from the theoretical deposition equations. In order to be able to evaluate the deposition equations, deposition experiments have been carried out with two models made of glass. The first model imitates the actual lung structure and the second model the lung model of Weibel (1963). Both models consist of the mouth up to and including the 6th generation according to Weibel's model. The distribution of the deposition of two polydisperse aerosols in these models is measured with a radioactive method, using 99inTc as a tracer after a constant inhalation of 8.0 or 16.0 1/min. As a result, the deposition in the mouth and oropharynx is ascribed to impaction while the deposition in the different generations can be explained by laminar sedimentation and diffusion. Using a division of the polydisperse aerosol into 13 monodisperse aerosols, the theoretical deposition is calculated. The results show that deposition in the different generations at these airflows is approximated within 25% using the exact solutions for a laminar airflow. Including impaction, as calculated with formulae found in literature, values for the deposition are calculated which are much too high (between a factor of 1.9 and 14). It is concluded that the impaction is the main problem in explaining these results." @default.
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- W1970168579 date "1977-12-01" @default.
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- W1970168579 title "Deposition of polydisperse aerosols in two glass models representing the upper human airways" @default.
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- W1970168579 doi "https://doi.org/10.1016/0021-8502(77)90035-0" @default.
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