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• W1970176959 abstract "Although acquired idiopathic thrombotic thrombocytopenic purpura (ai-TTP) is rare in children, the authors present the case of a 9-month-old boy with ai-TTP showing severe deficiency of ADAMTS13 activity by its inhibitory IgG-autoantibody (4.8 Bethesda units/mL). Plasma exchange therapy was clinically effective but transient. Deficient activity of ADAMTS13 with the presence of its inhibitor persisted for 7 months after the initial diagnosis. However, other laboratory findings improved gradually with steroid (pulse) therapy. The hitherto insufficiently characterized clinical settings of ai-TTP during early childhood underscore the importance of measuring ADAMTS13 activity and its inhibitors for differential diagnosis in patients with thrombocytopenia of unknown etiology." @default.
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• W1970176959 date "2010-02-02" @default.
• W1970176959 modified "2023-09-25" @default.
• W1970176959 title "A 9-MONTH-OLD INFANT WITH ACQUIRED IDIOPATHIC THROMBOTIC THROMBOCYTOPENIC PURPURA CAUSED BY INHIBITORY IgG-AUTOANTIBODY TO ADAMTS13" @default.
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• W1970176959 doi "https://doi.org/10.3109/08880010903401752" @default.
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