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• W1970182368 abstract "There is high interest in the discovery of early diagnostic biomarkers of Alzheimer's disease, for which metabolomics exhibits a great potential. In this work, a metabolomic approach based on ultrafiltration and analysis by CE‐MS has been used to obtain representative fingerprints of polar metabolites from serum samples in order to distinguish between patients with Alzheimer's disease, mild cognitive impairment, and healthy controls. By the use of partial least squares discriminant analysis it was possible to classify patients according to the disease stage and then identify potential markers. Significant increase was observed with progression of disease in levels of choline, creatinine, asymmetric dimethyl‐arginine, homocysteine‐cysteine disulfide, phenylalanyl‐phenylalanine, and different medium chain acylcarnitines. On the other hand, asparagine, methionine, histidine, carnitine, acetyl‐spermidine, and C5‐carnitine were reduced in these serum samples. In this way, multiple essential pathways were found implicated in the underlying pathology, such as oxidative stress or defects in energy metabolism. However, the most interesting results are related to the association of several vascular risk factors with Alzheimer's disease." @default.
• W1970182368 created "2016-06-24" @default.
• W1970182368 creator A5014346426 @default.
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• W1970182368 creator A5072585524 @default.
• W1970182368 creator A5085775380 @default.
• W1970182368 date "2014-10-09" @default.
• W1970182368 modified "2023-10-15" @default.
• W1970182368 title "Metabolomic profiling of serum in the progression of Alzheimer's disease by capillary electrophoresis-mass spectrometry" @default.
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• W1970182368 cites W1492443634 @default.
• W1970182368 cites W1935104830 @default.
• W1970182368 cites W1936038923 @default.
• W1970182368 cites W1963945829 @default.
• W1970182368 cites W1964045660 @default.
• W1970182368 cites W1967203590 @default.
• W1970182368 cites W1968419890 @default.
• W1970182368 cites W1978557401 @default.
• W1970182368 cites W1981132320 @default.
• W1970182368 cites W1981686145 @default.
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• W1970182368 cites W1986819054 @default.
• W1970182368 cites W1987892912 @default.
• W1970182368 cites W1990761051 @default.
• W1970182368 cites W1991459590 @default.
• W1970182368 cites W1993121582 @default.
• W1970182368 cites W1995578126 @default.
• W1970182368 cites W1997186669 @default.
• W1970182368 cites W2002640488 @default.
• W1970182368 cites W2003588313 @default.
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• W1970182368 cites W2005856400 @default.
• W1970182368 cites W2007466714 @default.
• W1970182368 cites W2013850100 @default.
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• W1970182368 cites W2035680108 @default.
• W1970182368 cites W2038034523 @default.
• W1970182368 cites W2041255286 @default.
• W1970182368 cites W2050518116 @default.
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• W1970182368 cites W2052588755 @default.
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• W1970182368 doi "https://doi.org/10.1002/elps.201400196" @default.
• W1970182368 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25136972" @default.
• W1970182368 hasPublicationYear "2014" @default.
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