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- W1970188265 startingPage "93" @default.
- W1970188265 abstract "Restoration of blood flow following ischemic stroke can be achieved by means of thrombolysis or mechanical recanalization. However, for some patients, reperfusion may exacerbate the injury initially caused by ischemia, producing a so-called cerebral reperfusion injury. Multiple pathological processes are involved in this injury, including leukocyte infiltration, platelet and complement activation, postischemic hyperperfusion, and breakdown of the blood-brain barrier.Magnetic resonance imaging (MRI) can provide extensive information on this process of injury, and may have a role in the future in stratifying patients' risk for reperfusion injury following recanalization. Moreover, different MRI modalities can be used to investigate the various mechanisms of reperfusion injury. Antileukocyte antibodies, brain cooling and conditioned blood reperfusion are potential therapeutic strategies for lessening or eliminating reperfusion injury, and interventionalists may play a role in the future in using some of these therapies in combination with thrombolysis or embolectomy. The present review summarizes the mechanisms of reperfusion injury and focuses on the way each of those mechanisms can be evaluated by different MRI modalities. The potential therapeutic strategies are also discussed." @default.
- W1970188265 created "2016-06-24" @default.
- W1970188265 creator A5026699335 @default.
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- W1970188265 creator A5039814584 @default.
- W1970188265 creator A5070078187 @default.
- W1970188265 creator A5081582230 @default.
- W1970188265 date "2006-12-20" @default.
- W1970188265 modified "2023-10-10" @default.
- W1970188265 title "Reperfusion injury following cerebral ischemia: pathophysiology, MR imaging, and potential therapies" @default.
- W1970188265 cites W1545877367 @default.
- W1970188265 cites W1546165821 @default.
- W1970188265 cites W1655344346 @default.
- W1970188265 cites W1773516416 @default.
- W1970188265 cites W1964349082 @default.
- W1970188265 cites W1964564262 @default.
- W1970188265 cites W1965159815 @default.
- W1970188265 cites W1965162744 @default.
- W1970188265 cites W1965693998 @default.
- W1970188265 cites W1966185899 @default.
- W1970188265 cites W1968025334 @default.
- W1970188265 cites W1968594920 @default.
- W1970188265 cites W1969478524 @default.
- W1970188265 cites W1970861490 @default.
- W1970188265 cites W1971924425 @default.
- W1970188265 cites W1972042674 @default.
- W1970188265 cites W1973192371 @default.
- W1970188265 cites W1973352521 @default.
- W1970188265 cites W1985043821 @default.
- W1970188265 cites W1990823228 @default.
- W1970188265 cites W1994993023 @default.
- W1970188265 cites W1996802760 @default.
- W1970188265 cites W1997255414 @default.
- W1970188265 cites W1998200062 @default.
- W1970188265 cites W2001461351 @default.
- W1970188265 cites W2003188614 @default.
- W1970188265 cites W2005305441 @default.
- W1970188265 cites W2010229920 @default.
- W1970188265 cites W2010381370 @default.
- W1970188265 cites W2013303926 @default.
- W1970188265 cites W2014467431 @default.
- W1970188265 cites W2015085032 @default.
- W1970188265 cites W2016198009 @default.
- W1970188265 cites W2016658085 @default.
- W1970188265 cites W2017408459 @default.
- W1970188265 cites W2020138738 @default.
- W1970188265 cites W2030188214 @default.
- W1970188265 cites W2030832161 @default.
- W1970188265 cites W2032655736 @default.
- W1970188265 cites W2034827296 @default.
- W1970188265 cites W2034941414 @default.
- W1970188265 cites W2035569448 @default.
- W1970188265 cites W2036827636 @default.
- W1970188265 cites W2041554790 @default.
- W1970188265 cites W2052858793 @default.
- W1970188265 cites W2060560910 @default.
- W1970188265 cites W2060821715 @default.
- W1970188265 cites W2061609991 @default.
- W1970188265 cites W2062642814 @default.
- W1970188265 cites W2065001847 @default.
- W1970188265 cites W2067436359 @default.
- W1970188265 cites W2069331655 @default.
- W1970188265 cites W2073826444 @default.
- W1970188265 cites W2074645321 @default.
- W1970188265 cites W2076690232 @default.
- W1970188265 cites W2078746887 @default.
- W1970188265 cites W2086434994 @default.
- W1970188265 cites W2091759075 @default.
- W1970188265 cites W2092078486 @default.
- W1970188265 cites W2093203591 @default.
- W1970188265 cites W2093455013 @default.
- W1970188265 cites W2096336546 @default.
- W1970188265 cites W2096940309 @default.
- W1970188265 cites W2099026857 @default.
- W1970188265 cites W2099399994 @default.
- W1970188265 cites W2100186853 @default.
- W1970188265 cites W2103386950 @default.
- W1970188265 cites W2103822801 @default.
- W1970188265 cites W2104869294 @default.
- W1970188265 cites W2109726055 @default.
- W1970188265 cites W2130143178 @default.
- W1970188265 cites W2136181617 @default.
- W1970188265 cites W2139893186 @default.
- W1970188265 cites W2142835803 @default.
- W1970188265 cites W2143174608 @default.
- W1970188265 cites W2146941721 @default.
- W1970188265 cites W2150968653 @default.
- W1970188265 cites W2151696914 @default.
- W1970188265 cites W2153595356 @default.
- W1970188265 cites W2154242056 @default.
- W1970188265 cites W2155215582 @default.
- W1970188265 cites W2157521028 @default.
- W1970188265 cites W2183353764 @default.
- W1970188265 cites W2185212891 @default.
- W1970188265 cites W2189111413 @default.
- W1970188265 cites W2229772813 @default.
- W1970188265 cites W2291944082 @default.
- W1970188265 cites W2292308933 @default.