FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970203721> ?p ?o ?g. }

• W1970203721 endingPage "573" @default.
• W1970203721 startingPage "566" @default.
• W1970203721 abstract "The main objective of this study was to elucidate the extent of hepatic oxidative stress following oral administration of zerumbone against monosodium iodoacetate induced Osteoarthritis (OA) in rats by monitoring microsomal cytochrome P450 and glutathione S-transferase enzymes as well as determination of oxidative stress biomarkers i.e., glutathione and malondialdehyde. Forty rats were randomly assigned into five groups. Rats in the first and second groups were treated with two different doses of zerumbone. Rats in the third group (positive control) were given celecoxib whereas the fourth group (negative control) was given corn oil. Rats of the fifth group were untreated not induced with OA and were used as a basal group. Results showed significant induction of cytochrome P450 and glutathione S-transferase and insignificant changes in both glutathione and lipid peroxidation levels in zerumbone treated groups compared to corn oil and basal groups. Levels of ALT and AST in zerumbone treated groups were comparable to the level in the basal group indicating absence of liver damage. Prostaglandin E2 level significantly reduced following zerumbone administration. Safety profile of zerumbone in this study, attract new investigation to explore its advantageous effect on using higher dosage regimen and/or longer duration against OA or other disease." @default.
• W1970203721 created "2016-06-24" @default.
• W1970203721 creator A5038065217 @default.
• W1970203721 creator A5045295690 @default.
• W1970203721 creator A5056724034 @default.
• W1970203721 creator A5082597299 @default.
• W1970203721 date "2011-05-01" @default.
• W1970203721 modified "2023-09-24" @default.
• W1970203721 title "Response of Hepatic Metabolizing Enzymes and Oxidative Stress in Orally Administrated Zerumbone Against MIA-Induced Osteoarthritis in Rats" @default.
• W1970203721 cites W1531212948 @default.
• W1970203721 cites W1971219594 @default.
• W1970203721 cites W1983310681 @default.
• W1970203721 cites W2009267289 @default.
• W1970203721 cites W2021051993 @default.
• W1970203721 cites W2024515089 @default.
• W1970203721 cites W2029936801 @default.
• W1970203721 cites W2048585854 @default.
• W1970203721 cites W2053031729 @default.
• W1970203721 cites W2054985969 @default.
• W1970203721 cites W2056233305 @default.
• W1970203721 cites W2056735841 @default.
• W1970203721 cites W2057699079 @default.
• W1970203721 cites W2059521247 @default.
• W1970203721 cites W2069384815 @default.
• W1970203721 cites W2084015464 @default.
• W1970203721 cites W2087547504 @default.
• W1970203721 cites W2088311820 @default.
• W1970203721 cites W2091528050 @default.
• W1970203721 cites W2138600916 @default.
• W1970203721 cites W2143160733 @default.
• W1970203721 cites W2162932896 @default.
• W1970203721 doi "https://doi.org/10.3923/javaa.2011.566.573" @default.
• W1970203721 hasPublicationYear "2011" @default.
• W1970203721 type Work @default.
• W1970203721 sameAs 1970203721 @default.
• W1970203721 citedByCount "4" @default.
• W1970203721 countsByYear W19702037212015 @default.
• W1970203721 countsByYear W19702037212016 @default.
• W1970203721 crossrefType "journal-article" @default.
• W1970203721 hasAuthorship W1970203721A5038065217 @default.
• W1970203721 hasAuthorship W1970203721A5045295690 @default.
• W1970203721 hasAuthorship W1970203721A5056724034 @default.
• W1970203721 hasAuthorship W1970203721A5082597299 @default.
• W1970203721 hasBestOaLocation W19702037212 @default.
• W1970203721 hasConcept C126322002 @default.
• W1970203721 hasConcept C134018914 @default.
• W1970203721 hasConcept C181199279 @default.
• W1970203721 hasConcept C185592680 @default.
• W1970203721 hasConcept C2776151105 @default.
• W1970203721 hasConcept C2777056448 @default.
• W1970203721 hasConcept C2778024521 @default.
• W1970203721 hasConcept C2778206080 @default.
• W1970203721 hasConcept C2778401633 @default.
• W1970203721 hasConcept C2779306644 @default.
• W1970203721 hasConcept C2780829032 @default.
• W1970203721 hasConcept C538909803 @default.
• W1970203721 hasConcept C55493867 @default.
• W1970203721 hasConcept C71924100 @default.
• W1970203721 hasConcept C98274493 @default.
• W1970203721 hasConceptScore W1970203721C126322002 @default.
• W1970203721 hasConceptScore W1970203721C134018914 @default.
• W1970203721 hasConceptScore W1970203721C181199279 @default.
• W1970203721 hasConceptScore W1970203721C185592680 @default.
• W1970203721 hasConceptScore W1970203721C2776151105 @default.
• W1970203721 hasConceptScore W1970203721C2777056448 @default.
• W1970203721 hasConceptScore W1970203721C2778024521 @default.
• W1970203721 hasConceptScore W1970203721C2778206080 @default.
• W1970203721 hasConceptScore W1970203721C2778401633 @default.
• W1970203721 hasConceptScore W1970203721C2779306644 @default.
• W1970203721 hasConceptScore W1970203721C2780829032 @default.
• W1970203721 hasConceptScore W1970203721C538909803 @default.
• W1970203721 hasConceptScore W1970203721C55493867 @default.
• W1970203721 hasConceptScore W1970203721C71924100 @default.
• W1970203721 hasConceptScore W1970203721C98274493 @default.
• W1970203721 hasIssue "5" @default.
• W1970203721 hasLocation W19702037211 @default.
• W1970203721 hasLocation W19702037212 @default.
• W1970203721 hasOpenAccess W1970203721 @default.
• W1970203721 hasPrimaryLocation W19702037211 @default.
• W1970203721 hasRelatedWork W1982601245 @default.
• W1970203721 hasRelatedWork W1982995414 @default.
• W1970203721 hasRelatedWork W1989789375 @default.
• W1970203721 hasRelatedWork W1990761779 @default.
• W1970203721 hasRelatedWork W2040712997 @default.
• W1970203721 hasRelatedWork W2094227734 @default.
• W1970203721 hasRelatedWork W2183986908 @default.
• W1970203721 hasRelatedWork W2754551828 @default.
• W1970203721 hasRelatedWork W2760841041 @default.
• W1970203721 hasRelatedWork W2901250264 @default.
• W1970203721 hasRelatedWork W2935929836 @default.
• W1970203721 hasRelatedWork W2938697408 @default.
• W1970203721 hasRelatedWork W2969603814 @default.
• W1970203721 hasRelatedWork W3013375652 @default.
• W1970203721 hasRelatedWork W3115846073 @default.
• W1970203721 hasRelatedWork W3132799820 @default.
• W1970203721 hasRelatedWork W3200646613 @default.
• W1970203721 hasRelatedWork W2146107853 @default.
• W1970203721 hasRelatedWork W2184069893 @default.

• next